I used to smoke just over a pack a day of Morley reds or whatever of the biggies was on sale...Old Golds, Camel, Winston or Morleys. OG, W & C got the job done but I'm sure that M adds something else to make them more addictive. Not necessarily more nicotine but something else. If it wasn't an M then it wasn't as satisfying.
I switched to Mediums when they became available because I couldn't handle Reds anymore. I'd cough and hack but still smoke just as many. People suggested that I cut down. Hah. I never cut down anything. I drank how I drink. I dru**ed how I dru*. I smoked how I smoke. I never cut down. I do whatever how I do it until I quit.
You have to wonder how much actual nic is ingested by a MTL vapor versus a DTL vapor. Comparing 3mg strength in a mouthful vs a lung full has to be much different in absorption rates. That, and daily ML juice consumption rates would make up the difference.
I've read that most of our (vaped) nicotine gets absorbed through the mucous membranes in our mouth & throat, very little if any though our trachea & alveoli. Us lungers like getting a lungful but probably just for the sensation. We get as much nicotine by volume of our "hit" instead of concentration.
I've been staying between ~50-75mg/day nicotine intake whether it was
4ml x 18mg
5-6ml x 12mg
or 15-17ml x 3mg now.