Definitely better build quality. In that respect, I'd say there is really no comparison.
The internal engineering and craftsmanship of the SXmini is comparable to the finest devices on the market. Quality through and through.
As far as the actual boards go, the SX330 in Power mode does not offer true buck circuitry, and delivers a PWM signal to achieve lower voltages, and a DC-DC signal at higher voltages. The SX350J of the SXmini M Class offers true buck/boost circuitry and delivers a flat DC signal regardless of the voltage output. The accuracy of the SX350J puts it up there with some of the most accurate devices on the market, right on par with the
dna and ProVari. The SX330 boards do not achieve that level of accuracy.
EDIT: I will add here that the SXmini DOES have the option of adding a second battery in series that boosts the power delivery up to 120W. It looks ridiculous, and if you NEED something above 60W in a device, I would personally stick with the dual battery mods like the iPV4 / Sigelei mods just cause the battery extension on an SXmini looks like a freak show. Plus, if you're routinely using the device above 60W in power mode, you won't be experiencing the PWM rattlesnake vape anyway. All that said, if you can get a dual 18650 custom mod that shares a similar form factor to the iPV / Sigelei boxes (side by side
batteries) with an SX350J board, I would go with that over the SX330 V4S option.
As far as the SX330 V4S board in temp limiting mode, I can't speak for that. I would assume that they perform similarly, but take in to account that the SX330 won't be as accurate as the SX350 with regards to voltage delivery.
The biggest difference though with price is going to be in materials, engineering and craftsmanship of the mod itself. It's difficult to see in pictures but blatantly obvious in the hand. The SXmini is built MUCH better than any iPV or Sigelei mod. MUCH better...