Most of the time I either use the same juice in a tank or wait until all the juice is gone before switching flavors. However, I have what I call my mad scientist tank that I randomly mix new flavors into as I go resulting in a suicide of flavors. Right now I have mt dew, bubble gum, blue voodoo, a touch of menthol and mister e energy in random quantities in the tank and the vape is amazing. Does anyone else have a dedicated mad scientist tank? Just bored at work and making random conversation =)