This depends upon your definition of "Un-protected".
If you mean
un-protected Li Ion batteries, NO! You should never use an un-protected Li Ion battery in a mechanical mod. Mechanical mods have zero protection built into the mod. YOU are the protection - the protection depends upon your better judgement and common sense. Regulated mods that use processors to increase voltage have built-in protection to make them safer.
IMR (Li Mn safe chemistry) are sometimes erroneously called un-protected, too. These use a safer chemistry not requiring a protected circuit. IMR batteries are what are currently recommended to be used in all mods, regulated or mechanical, over
protected Li Ion. http://www.e-cigarette-forum.com/forum/ecf-library/129569-rechargeable-batteries.html)
Protected batteries are Li Ion batteries with built-in protected circuits, however should the simple circuit fail, then the battery can fail, too.
Un-protected batteries are NEVER recommended. (resource:
Li Ion battery chemistry is very unstable and volatile (flamable) if stressed. Battery failure can lead to venting hot flames and extreme pressure within the mod. A collapsable hot spring and vent holes provide little safety as a failing battery can swell, blocking off venting of the safety holes in the mod.
IMR batteries can fail and vent, too. However, their chemistry allows them to be more tolerable to stress and less likely to vent in flame or extreme pressure. This IMR battery recently failed in a backpack, probably because it made connection with another battery in the pocket. Luckily it was an IMR and not a Li Ion battery as there was no flame involved.
http://www.e-cigarette-forum.com/forum/new-members-forum/472990-hi-all-shaken-up-provari-aw-18490-battery-owner.html
Battery Basics for Mods: IMR or Protected?