e-cigs vs. Nicotrol Inhaler Stats

[Spikey]

*** mods.. feel free to edit for language.. tried to *** the bad words. But PLEASE do not remove content!!! This info will be VERY useful in the fight against the FDA!!! (if they don't find this post and delete it.. yes I am paranoid)

Below this link are posts from this thread on another forum. Posts are copied from myself and one other poster who provided a VERY valuable link to the nicotrol inhaler studies.

WHERE is the (#$*(%? NJoy Study?!? - Vapers Forum

Spikey:U want war??? I got WAR!!!

Found some GREAT ammo for the HHSC meeting tomorrow!!!!!

Ok.. so get this...

Nicotrol inhalers (AN FDA APPROVED NRT!!!!) contain nicotine suspended in pyridine.

From Wikipedia: Pyridine was originally industrial produced by extraction from
Coal_tar


Now it is synthesized from: Formaldehyde
, Ammonia , Acetaldehyde


Ohhh. can you say TOXINS????

Each Nicotrol Inhaler Cartridge contains 10MG nic. Only 4MG actually get used. Only TWO MG of nic get "systematically absorbed". What the .... do you think happens to the OTHER TWO???

Leg Cooper.. your argument is figuratively in the sh*tter!!!!

PG has been studied for SIXTY years and was found not to be toxic and is FDA approved.

Does anyone know if formaldehyde, ammonia and acetaldehyde are FDA approved??? Anybody??? (acetaldehyde is coincidentally the toxin found by ruyan in the NZ styudy which was in such minute amounts it was below FDA standards for safety).

Ok... so less safe delivery system, carrier liquid proven to be toxic and higher nicotine dosage into the air because of cooler temps (nic is said to not reach lower respiratory tract meaning poorer absorption than with vapor)... BUT....

FDA APPROVED FOR INDOOR USE!!!

Hello??? Duh???

Ok... now for the TSNA stats... I need the ORIGINAL study done for FDA approval on the Nicotrol Inhaler.

Get to work people!!! Search that FDA website til we find it! I CANNOT sleep wil we do.. I NEED those stats!!


Ridewithme38: This looks right...i can't view pdf's though

http://www.accessdata.fda.gov/drugsa...cotrol_toc.cfm

Spikey: To all else who actually READ the FDA study (on e-cigs)???
The reason the TSNA stats for nicotrol inhaler (which was their CONTROL in the study) were absent??? They haven't F*CKING tested them yet!!! Are ya F*CKIN KIDDING ME????

Holy sh*t!

I have just busted my as$ for the stats to prove the FDA approved nicotrol inhaler is less safe and guess f*cking what? I CAN'T cause they DIDN'T F*CKING TEST IT for carcinogens!!! They approved the f*cking thing without testing if it caused ****ing cancer!! GOD I LOVE THE "FD f*ckin' A"!!!!

OK.. stats pulled from FDA study on Nicotrol Inhaler...

-Nicotine is expected to biodegrade if released into auir, water and soil. Nicotine is not expected to bioaccumulate significantly.

-The Nicotrol Inhaler is not expected to alter significantly the concentration of nicotine, it's metabolites, degradation products, or it's constituent parts in the environment.

-...the small amount of nicotine emitted into the environment is well below levels associated with adverse effects...

-Nicotine has been found in drinking water in several US cities

-The average nicotine exposure levels in public places range from 0.031 to 0.043 mg/cubic meter. The Threshhold Limit Value (TLV) for nicotine is 0.5 mg/cubic meter (ACGIH, 1990)

-Nicotine is expected to degrade quickly in the presence of light and oxygen (thus keep juice in cool, dry, dark place!)

-pg 25 of FDA Chem stat sheet shows mg nic per puff off the nicotrol inhaler and for marlboros. That can be compared (if you change measurements in new e-cig study) to the nic per puff in new study... but check the "puff" size/length to make sure it is comparable. Will not be able to think enough to do this tonight. Will do tomorrow.

PM me if you need page number info on the stats for writing of articles.

 

[Krakkan]

Awesome Spikey

 

[Boom!]

Beautiful! Thank you so much and I will continue to spread the word. This isn't nearly over!

 

[Our House]

Amazing, really.

 

[NY JETS]

Spikey for president!

 

[souporvapor]

The chemical name/structural formula for the Nicotrol Nicotine inhaler - from the pdf's in the link provided) is
S-3(1methyl - 3 pyrrolidinyl) pyridine

From wikipedia -
Pyridine is harmful if inhaled, swallowed or absorbed through the skin.[11] Effects of an acute pyridine intoxication include dizziness, headache, nausea and anorexia. Further symptoms include abdominal pain and pulmonary congestion.[12] Currently its evaluations as a possible carcinogenic agent showed there is inadequate evidence in humans for the carcinogenicity of pyridine, albeit there is limited evidence of carcinogenic effects on animals.[12] Available data indicate that "exposure to pyridine in drinking-water led to reduction of sperm motility at all dose levels in mice and increased estrous cycle length at the highest dose level in rats".[12] The LD50 in rats (oral) is 891 mg kg–1. Pyridine is highly flammable and its vapour will spontaneously ignite in air at room temperature.[11] Pyridine is readily degraded by bacteria to ammonia and carbon dioxide.[13]

Guess they weren't trying to hide anything there - came right out with the chemical formula specifically detailing major component

Role in chemical synthesis:
Pyridine is an important solvent and reagent in organic synthesis.[9] It is used as a solvent in Knoevenagel condensations. It is the precursor to myriad insecticides, herbicides, pharmaceuticals, food flavorings, dyes, rubber chemicals, adhesives, paints, explosives and disinfectants. Examples include paraquat[1]

From what I can find in the report - there was never any testing for 'what's in it'.
The tests were monitoring the success rate of smoking cessation with all the details of the results, discovering toxicity if swallowed/eaten and others related to performance of the product rather than ingredients in it.
They also tested for nicotine content - doesn't look like any concern at all over 'other ingredients'



'sponsors' who presented the study results: Pharmacia and Upjohn Company

GO SPIKEY!!!! Thanks - I tried to get this information (and on other NRT's ) from the American Lung Association ----- not the right place to look I guess.


Hang in there lady - you are AWESOME!

 

[solonguniverse]

The chemical name/structural formula for the Nicotrol Nicotine inhaler - from the pdf's in the link provided) is
S-3(1methyl - 3 pyrrolidinyl) pyridine

From wikipedia -
Pyridine is harmful if inhaled, swallowed or absorbed through the skin.[11] Effects of an acute pyridine intoxication include dizziness, headache, nausea and anorexia. Further symptoms include abdominal pain and pulmonary congestion.[12] Currently its evaluations as a possible carcinogenic agent showed there is inadequate evidence in humans for the carcinogenicity of pyridine, albeit there is limited evidence of carcinogenic effects on animals.[12] Available data indicate that "exposure to pyridine in drinking-water led to reduction of sperm motility at all dose levels in mice and increased estrous cycle length at the highest dose level in rats".[12] The LD50 in rats (oral) is 891 mg kg–1. Pyridine is highly flammable and its vapour will spontaneously ignite in air at room temperature.[11] Pyridine is readily degraded by bacteria to ammonia and carbon dioxide.[13]

Guess they weren't trying to hide anything there - came right out with the chemical formula specifically detailing major component

Role in chemical synthesis:
Pyridine is an important solvent and reagent in organic synthesis.[9] It is used as a solvent in Knoevenagel condensations. It is the precursor to myriad insecticides, herbicides, pharmaceuticals, food flavorings, dyes, rubber chemicals, adhesives, paints, explosives and disinfectants. Examples include paraquat[1]

From what I can find in the report - there was never any testing for 'what's in it'.
The tests were monitoring the success rate of smoking cessation with all the details of the results, discovering toxicity if swallowed/eaten and others related to performance of the product rather than ingredients in it.
They also tested for nicotine content - doesn't look like any concern at all over 'other ingredients'



'sponsors' who presented the study results: Pharmacia and Upjohn Company

GO SPIKEY!!!! Thanks - I tried to get this information (and on other NRT's ) from the American Lung Association ----- not the right place to look I guess.


Hang in there lady - you are AWESOME!

They might be trying to attack this addiction thing from a new angle...by just giving us the carcinogens we crave.

 

[HighTech]

God I love the internet! Nice work!

 

[chad]

Nicotrol inhalers (AN FDA APPROVED NRT!!!!) contain nicotine suspended in pyridine.

Coal Tar Extract!? That crap's in my dandruff shampoo (I was amazed at that fact when I read it on the back of the bottle years ago) and it smells pretty nasty!

Uggh. Well, at least they tested those Nicotrol inhalers for carcinogens...

I have just busted my as$ for the stats to prove the FDA approved nicotrol inhaler is less safe and guess f*cking what? I CAN'T cause they DIDN'T F*CKING TEST IT for carcinogens!!! They approved the f*cking thing without testing if it caused ****ing cancer!! GOD I LOVE THE "FD f*ckin' A"!!!!

What!?!? Oh, no! Well, thankfully they tested vapes! Whew, I thought for a second they weren't worried about keeping me safe.

Nice going Spikey!! You're the ma... err... WOMAN!!

 

[Stranger]

Wow. That is damning. I hope this makes it to court. If I here one more person going on about how the Ruyan cartridge study doesn't count because they paid for it I can show them this:
'sponsors' who presented the study results: Pharmacia and Upjohn Company

This also might set a precinct for taxation. I know that Nicitrol is sold as a cessation device but what do you want to bet some people are using it with no intentions of stopping.

 

[seminolewind]

Now how do we get this info out to the public who are not members of these forums???

 

[Mach10X]

This also might set a precinct for taxation. I know that Nicitrol is sold as a cessation device but what do you want to bet some people are using it with no intentions of stopping.

I wish I could find the article that states that Nicotrol Inhaler prescriptions are to be limited, so a heavy smoker couldn't be using it as often as he would normally smoke. I think that doctors are required to reduce the number of refills...so guess what happens? Yes, people will blow through all their Nicotrol Cartridges then sit there craving nicotine and decide to light up an analog since they're required by law to wait a certain period to get a refill on their inhaler.

 

[seminolewind]

it's always the same song. People who have never done ___ make the plans or items for people who do, and they don't work. You don't think that those cessation aids were invented by smokers, do you?

Reminds me of my job. I work with babies in incubators. The incubator glass has a curve to it at the point that you look thru. To top that off, it catches the glare so bad that we continuously have to move our heads all over to see the patient without curvy glass or glare. Do ya think one of us nurses designed that?

 

[seadooman]

Spikey for president!

I second that.

 

[chad]

Reminds me of my job. I work with babies in incubators. The incubator glass has a curve to it at the point that you look thru. To top that off, it catches the glare so bad that we continuously have to move our heads all over to see the patient without curvy glass or glare. Do ya think one of us nurses designed that?

Nice. Therein lies the "real" problem with most laws today. Written by people out of touch, approved by people who convince each other they're right, enforced by people who take them too literally. Very nice example seminolewind!

 

[seminolewind]

Thanks Chad, it's been an irritation for 17 years now.