It really depends on the power device you are using mate. If you've got variable volts/watts then it doesn't really matter. But if you've got a flat signal then the resistance will determine the heat/power/vapour etc that you get. So if you haven't got variable power then you pick the resistance you prefer as in hotter vape = lower resistance.
Dunno about the holes you are talking about - do you mean adjustable airflow? Because the aerotank has that.