Depending on what juice you're using and its flavor compatibility, you don't have to wait until its empty... that's risky business anyway... just start topping it off with a few drops. Stay by the wall and try to avoid getting juice in the center hole (air shaft) but if you do get some in there just blow on it with your top lip only and it will clear out. You'll be able to tell by taste and vapor production how many drops. Start with ... oh... 5 drops, up to 8 drops, then 12 and so on. Eventually you might even get to 15 and then you've pretty much totally refilled it. If you do overdo and get a gurgle instead of a crackle hitting the power, then blow on it from the threaded end and blow some juice out on a kleenex... no biggy. After that you might need to set it upright for a half hour to totally absorb the juice. Hope that helps.