I just use mine until they feel anemic and give a shorter use cycle. If I suspect a battery of getting tired, I put an X on it and keep an extra eye on it to make sure it's not just my imagination. At that point I limit that battery to one setup - and only swap it out with one 'good' battery for comparison.
Not very scientific. Then again - for me it's all about how the vape feels, not so much about numbers. If something consistently don't work as it should, it's done.
(This is with mechs as well. How long they last between charges should be a good indicator on regulated mods as well)