I smoked at least 22 marlboro lights a day. Six or more at my desk before leaving for work. (two or three hours). I have to say there is no way I get the same nic from equal time e-smoking. I would have a pulse rate in the mid to upper 90s with analogs. I am rarely above 70 even when almost chain-smoking the ecig. That is with 24mg juice. I am doing a personal study with time and amounts in drops to see exactly where I stand.