No, dude. It does not fatigue my tastebuds and has no negative impact on food flavours for me. The only time I cannot taste Geoffs Blend is when I have a cold. That's when I switch over to TV's Honey Cough Drop with is very similar to the Halls Honey cough drop. Eucalyptus and Menthol with a Honey back-end. Perfect for stuffy nose and blocked sinuses. That juice cannot be vaped while I'm in normal health. The Menthol and Eucalyptus is way over powering. 