ibuprofen and vaping

[rolygate]

As far as I am aware, there are no interactions between the painkiller ibuprofen and nicotine / vaping / smoking, although there are some issues connected with chronic high dosage consumption of ibuprofen (and some other NSAIDs such as diclofenac). A recent study reported that daily high doses of ibuprofen can be associated with cardiac arrythmias or cardiac events. Therefore if you have a genetic predisposition to CVD (a family history of cardiac or vascular conditions, for example early death from stroke etc.) then you might wish to moderate ibuprofen or diclofenac intake.

The same thing might apply to nicotine intake: excess consumption may not be a good idea for some people.

In the case of a person consuming a comparatively large amount of an NSAID daily plus significant amounts of nicotine, they might want to be assured that CVD issues do not run in the family as there may be some risk elevation.

That's all.

As with any issue of this type, you would almost certainly be better off speaking to a doctor. Internet health advice may or may not be accurate.

 

[Katya]

It did and thanks. I think you and several others are correct. I think it was a combination or actual stress and nic being obtained in a new way. I have adjusted and feel much better

I'm glad you're feeling better.

FWIW, I've been vaping and taking ibuprofen for 5 years without noticing any ill effects. Having said that, I agree with other posters that too much of any drug is never a good thing. I use ibuprofen, naproxen sodium (aleve), aspirin and acetaminophen for pain and inflammation. They all work just fine.

Since you're a new vaper, you may find this information useful:

http://www.e-cigarette-forum.com/fo...hen-quitting-tobacco-changing-ecigarette.html

 

[Katya]

Just a note: nicotine is not a muscle relaxant. It activates the same receptors that cause the muscle contractions involved in voluntary movement.

It's also a vasoconstrictor that decreases blood flow to the tissues.

 

[rolygate]

In the medium/long term, nicotine is reported to reduce the blood pressure.

This is an interesting feature considering that in the media it is usually said to raise the blood pressure. To be completely accurate, acutely it raises the blood pressure, chronically it lowers it (at the time of consumption it raises blood pressure, since it is a vasoconstrictor, but over time it reduces it). Lowering of blood pressure is not just a long-term effect as it is reported after a few months in never-users of nicotine.

See Dr Newhouse of Vanderbilt's work. He is believed to be the leading expert on nicotine currently, as he has administered pure nicotine in clinical trials to more never-smokers than anyone else. See the vaping Quotes page on ecigarette-politics.com .

 

[Katya]

Thanks Roly! Very interesting. I didn't know that.

 

[rolygate]

Yes, a lot of new info is coming out on nicotine. All the old myths are being smashed. There are two reasons for that: the massive increase in interest in the topic generated by the vaping community, and its refusal to accept the usual lies; and the progress on use of nicotine in medicine.

Essentially, everything that was 'known' about nicotine has now been destroyed, as it mostly appears to be old myths. For example it cannot be shown to create dependence outside of delivery along with tobacco; it is now known to be about 20 times less toxic than previously believed; more people are aware it is a normal ingredient in the diet and everyone tests positive for it; and no clinically-significant harm can be shown to derive from long-term consumption.

There is only one more issue to investigate: although many people such as Dr Newhouse have shown that nicotine dependence cannot be created without tobacco, at least with delivery methods that don't include ecigs, it remains to be seen if any clinically-significant levels of dependence can be created by delivery with an ultra-efficient delivery system such as the ecig (as that delivery system is highly efficient and psychologically attractive). There are some people who think that something of this sort may be possible even though no other method of delivering pure nicotine can show any potential for dependence.

I don't think clinically-significant levels of dependence will be created (which is generally taken to mean more than 3% of subjects, repeated in multiple trials); and perhaps even statistically-identifiable levels will be hard to show (somewhere between 1% and 2% of subjects, repeatable). On the other hand it seems likely that *some* people may become dependent although perhaps not at a statistically-identifiable level. In other words, perhaps 5 or 6 in 1,000 or something like that (around 0.5%). Even so, It doesn't seem likely that this would be a difficult dependence to break, as there is no chemical 're-wiring' of the brain, unlike that which occurs in smoking (the MAOIs etc. cause a permanent or semi-permanent change in brain chemistry). Probably quite similar to tea or something like that - you'll miss it for maybe 3 or 4 days, but withdrawal does not produce strong cravings, and you can get over it if you want to.

Tobacco has a cocktail of potentiators and synergens, all of which are missing with ecigs. What's left is a strong, fast nicotine delivery system that is 'seductive' - easy to like and get attached to. But plenty of people give up vaping, after tailing off the nic, so vaping cessation would seem to be a minor issue compared to smoking cessation (if dependence is eventually shown to exist at all in identifiable numbers).

We won't know until many non-smokers have started with ecigs, and never smoked, then attempt to quit. That's probably several years down the line.