FDA If nicotine is so addictive...

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zapped

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At the 3 week mark after quitting cigarettes I had flu-like symptoms. My muscles ached constantly and were always tired like they the were being robbed of O2. I had massive cramps that raised my body off the bed as my muscles contracted (Im a guy) .I sweated and I had extremely vivid nightmares. This from someone who rarely remembers their dreams.

After a week or two these symptoms passed.I attribute this to the other 3999 chemicals in cigarettes leaving my body. I smoked 2 packs a day for 25 years so my reaction may have been stronger than others as these chemicals had time to build-up.

The good news is I've been vaping 0 percent nicotine for a week now after 18 months without a single cigarette and Im showing no ill effects or cravings.

The hand-to-mouth might prove to be more difficult to give up with vaping than the nicotine.........and Im okay with that.
 

e30holmes

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Its the money.....the "free market" came up with a remarkable and potent quiting tool and the corporations that have a majority ownership of the market will fail and loose. In turn they decided it was best to keep their pockets full and team together to try and stop this market crashing solution. I would put my life savings on the idea that if one of the big tobacco or big Pharmacy corporations invented this idea there would be no problems. However if that was the case I do belive that it would also not be so fun and user friendly.

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FireDragon1138

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Warning labels are not required on NRT because NRT is marketed as a smoking cessation product. E-cigs are not, the industry cleverly ducks that claim because it would make e-cigs a medical device. So e-cigs and NRT have two different goals, one has a higher bar, the other one relatively low, with more risks to consumers with unknowns. I don't think labelling e-cigs as addictive is irresponsible at all.

Years ago I used nicotine lozenges and found I became dependent on them... so I switched to the patch and that cured that. I don't think the term "addictive" is misplaced if it is used in a non-technical sense and applied to nicotine.
 

Stosh

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.... Years ago I used nicotine lozenges and found I became dependent on them... so I switched to the patch and that cured that. I don't think the term "addictive" is misplaced if it is used in a non-technical sense and applied to nicotine.

Addictive behavior is usually defined as using a substance (drugs, alcohol) or performing an action (gambling) that is HARMFUL to the user, while ignoring any potential harm. Also the substance or action is needed in ever increasing doses to satisfy the addiction.

Cravings are more common and benign, such as caffeine, spicy food, nicotine.
 

Kent C

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Was doing the same. However when you create a molecule from others, the others are no longer there, it is the new molecule. I suppose it would be an issue only if the molecule degrades back into it composition constituents.

The MSDS yields

PYRIDINE:

I do understand.... just doing a bit of what the ANTZ do with eliquid :) And yet out bases of PG and VG sound much more safe then theirs.
 

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Rossum

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Rossum

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At the 3 week mark after quitting cigarettes I had flu-like symptoms. My muscles ached constantly and were always tired like they the were being robbed of O2. I had massive cramps that raised my body off the bed as my muscles contracted (Im a guy) .I sweated and I had extremely vivid nightmares. This from someone who rarely remembers their dreams.

After a week or two these symptoms passed.I attribute this to the other 3999 chemicals in cigarettes leaving my body.
Or maybe you actually did have the flu? :laugh:

Seriously, that sounds a bit extreme for smoking-withdrawal symptoms.
 

Rossum

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And... I was looking at the Nicotrol inhaler as a possible 'predicate' for substantial equivalence. since it is inhaling nicotine....

The nic base for Nicotrol inhalers (FDA APPROVED NRT) contain nicotine suspended in pyridine. (cut/paste from VF)
I think you're mis-reading something.

"Nicotine is a tertiary amine composed of a pyridine and a pyrrolidine ring."

That's a description of the nicotine molecule. It's not a statement that Nicotrol uses pyridine as a "carrier" for nicotine.
 

AndriaD

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Or maybe you actually did have the flu? :laugh:

Seriously, that sounds a bit extreme for smoking-withdrawal symptoms.

Yeah the cramps sounds more like the cramps I endure on pretty much a nightly basis, if I don't drink my powerade/tonic water "cocktail" every night. I mean I know the quinine is "cheating", but there is just so much water I can drink! I was starting to need either a catheter or a computer in the bathroom! ;) The "White Cherry" Powerade mixed with tonic water tastes somewhat like Mtn Dew CodeRed soda, which I love, but less sweet, which I also love -- and no caffeine to complicate the problem further! :thumb:

The negative feelings I suffered were a lot more subtle; at first I fell into the old trap of wondering why everyone seemed to hate me all of a sudden, then realized that nothing about *them* had changed, what had changed was *me* and my entire outlook on the world -- it's embarrassing to find yourself at 52 having feelings more suited to a 16 yr old who's sure that everyone else has the problem, not ME! :D And it really didn't take too long to pass, inside a week, though it's possible that the timely arrival of vapemail shinies helped improve my mood. ;) I think it was a Mini PT II, that time. But anyway, no nightmares whatever since I've started vaping/stopped smoking, and very few dreams related to smoking -- in fact, in the last one, when I felt that cigarette craving, my PV just magically appeared, as things do in dreams. I woke up right after that, with a smile, feeling confident that I've finally licked that #$%&%$%# of a habit.

:vapor:
Andria
 

zapped

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Or maybe you actually did have the flu? :laugh:

Seriously, that sounds a bit extreme for smoking-withdrawal symptoms.

No it wasnt the flu. No cough, no congestion, no stuffy head, nothing even remotely like that.... just the symptoms mentioned previously.

It felt more like a malaise than a flu.

Ive heard people mention carbon monoxide in association with cigarettes before and I know that it has an effect on our muscles.In a nutshell its what makes them get tired.

Maybe that was my bodies way of adjusting to much lower levels of it after so many years?
 
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Kent C

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I think you're mis-reading something.

"Nicotine is a tertiary amine composed of a pyridine and a pyrrolidine ring."

That's a description of the nicotine molecule. It's not a statement that Nicotrol uses pyridine as a "carrier" for nicotine.

It was a copy/paste job from VF, but I saw ethanol is also an inactive ingredient - although finding that wasn't easy. lol Menthol as well and nicotine but I would think it would have to have a base to dilute it, unless it's just ethanol - which is possible.
 

Anjaffm

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No it wasnt the flu. No cough, no congestion, no stuffy head, nothing even remotely like that.... just the symptoms mentioned previously.

It felt more like a malaise than a flu.

Sounds like a typical case of the blahs that people tend to get from withdrawals for all those other substances in tobacco smoke.
I know the feeling. Not the physical pain - I had none of that, thankfully - but this feeling like "Oh, I am not myself today. I do not feel well at all. As if I am coming down with something. .. Awww.. I am just not myself today... what on earth is wrong with me?" (*grumble* *mutter* *make face* *move around on chair*)

And yes, there are definitely withdrawals for those other substances in tobacco smoke.
And we vapers are very lucky that we can enjoy the handling and the nicotine and get over those blahs.
 

Anjaffm

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AndriaD

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Sounds like a typical case of the blahs that people tend to get from withdrawals for all those other substances in tobacco smoke.
I know the feeling. Not the physical pain - I had none of that, thankfully - but this feeling like "Oh, I am not myself today. I do not feel well at all. As if I am coming down with something. .. Awww.. I am just not myself today... what on earth is wrong with me?" (*grumble* *mutter* *make face* *move around on chair*)

And yes, there are definitely withdrawals for those other substances in tobacco smoke.
And we vapers are very lucky that we can enjoy the handling and the nicotine and get over those blahs.

I'm wondering if there's anything known about a particular upsurge in withdrawal-type feelings/behavior at the 10-wk pt. I didn't really feel any different yesterday, but it seemed like everything I said came out snippy, to the point that my husband was yelling at me to stop being such a... you know, witch with a B. :D I did feel somewhat "overburdened"... with whatever it was I was doing at any given time. To me it seems kinda like the grouchy, ill-tempered feelings normally associated with cold-turkey quitting. But no cravings, just the very subtle grouchy feeling, like "this is just more than I can deal with right now!" kind of feeling.

Andria
 

Stosh

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Sometimes it's not withdrawal from smoking or vaping or nicotine to blame at all. May just be you're having a bad day or week, nothing in particular but a feeling of life sucks and then you die....

@ Andria, tell your husband Dr.Stosh said to pick you up some prescription meds...a small bag of dark chocolate truffles, to be taken as needed......:laugh:.....it's worked for me from the husband point of view.
 

AndriaD

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Sometimes it's not withdrawal from smoking or vaping or nicotine to blame at all. May just be you're having a bad day or week, nothing in particular but a feeling of life sucks and then you die....

@ Andria, tell your husband Dr.Stosh said to pick you up some prescription meds...a small bag of dark chocolate truffles, to be taken as needed......:laugh:.....it's worked for me from the husband point of view.

Heh... sounds like good medicine, but I'm puzzled, are the chocolates for me or for him? :D

Nothing out of the ordinary going on, really, *except* the fact that I've quit smoking... that's why I thought maybe that was what was wrong with me -- I wasn't making an effort to be a witch-with-a-B, it just seemed that everything I said came out that way -- kinda like when I used to get PMS -- no real effort made, it just happened that way. When I'd get that response to anything I said, I'd wonder, what's wrong with me? and 9 times out of 10, it was PMS. Which stopped being part of my life more than 5 yrs ago, but now, I'm an ex-smoker, and pretty recently, so it naturally seemed to me that I might be suffering some pangs from it, but with the vaping, not really even realize it -- till I pi$$ed off my husband! ;)

Andria
 
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