Hah - good point.
What I meant is that apparently there is now some evidence that long-term abuse (over-consumption of the highest strengths) of NRTs can cause cardiac dysrythmia, with several cases in the literature, some serious (such as atrial fibrillation and similar conditions that may not be reversible). This is why I do not think it advisable to over-consume nicotine in the long term, especially for those in the group who have no symptoms of nicotine OD. Of course, one viewpoint is that if say 5 or 6 people have died from abuse of NRTs then this represents an extremely good safety profile for them, considering the numbers involved (pyschoactive drugs such as Chantix are not in this group - and are recognised as having significant danger). If e-cigarettes have such a profile it would be excellent.
It seems a good idea to me to find the lowest acceptable level of nicotine, instead of
vaping high strength liquid in the long term and never checking to see if you can go lower.
We have to accept that if the entire smoking population of ~60 million switched to e-cigarettes, some would still die. That number might be very low, as in the case of Snus users, and thus not really be statistically significant - i.e., it is just about visible at population level but the risk to any individual is extremely low.
Anyway, assuming that some will die, the question is - from what? One answer is abuse, in other words long-term over-consumption of high-strength materials. Another, I think, will be from lung complications for a sensitive minority. Although the numbers might be very low indeed, in order to keep a hold on reality it is necessary to accept that some mortality is inevitable.