PG/VG fog machines have an EPA workplace exposure level in the industry. People who work with fog machines in the movie and stage business are limited in the time they can be exposed to the fog in a workday.
PG is an irritant. VG has some issues with a "heavy lung" feeling for some when they vape too much VG. I sense the same thing when I vape more than 20% VG, but I like the vapor increase. I usually vape 100% PG and sometimes sense the slight irritation if I vape too heavily, but it's not as bad as the feeling I get if I add too much VG. Different atomizers have different levels of irritation. Some are just smoother and milder than others.
Face it, vaping is so much better than smoking that we are all better off vaping like smokestacks than smoking cigarettes, but limiting our exposure is also a good practice. I find myself vaping like a fiend at times, but it's good if I can put it down for a while and let my lungs rest. Clean air is better than smoking OR vaping and we all need some clean air time here and there.