I've never used any pod system, and I am unclear as to what defines high wattage. I guess the highest I've used for more than a draw or two was around 45, and surely that falls short.
What I have noticed when stepping up from 20 to 40 watts is much shorter battery charge and much higher consumption of eLiquid. Also, that it became necessary to reduce the nic level of the liquid at higher wattage.
It stands to reason that if you're consuming more liquid, you'd get more flavor from the same liquid formulation.
I don't know what defines low resistance either. I do have some sub-ohm coils, but the lowest are 0.4ohm. That's when I get to the neighborhood of 40 watts, maybe a bit higher.
It's obvious to me that it's not very economical. I've been satisfied for more than 10-years with reasonable ranges to never have any nic cravings, nor to even think about smoking again, ever. That's great, so far as I'm concerned.