I've done simple hot VG flavor extractions with coffee, a couple of
tobacco products, ground ginger, and ground cinnamon. I've considered doing cocoa and a few other things, as well.
All of these are dried and ground or shredded, which is probably what I'd do to any homegrown thing that I wanted to try. Not saying that it's the best way, just what seems easiest for the means that I have.
I've since dumped all but the cinnamon and ginger, which I use sparingly, and only occasionally.
The coffee was good, at first, but very dark with a fair amount of particulate. It was pretty hard on atomizers. I didn't like it much after it had set for a month or so, as the taste seemed to get kind of musky. I honestly can't imagine why that would happen, though.
The tobacco was also pretty good, and had less solid matter in it, but suffered the same fate as the coffee extract. I won't try either of these again with the same Humco Glycerin that I used before. I plan on revisiting them with a different source for VG.
The cinnamon and ginger flavors came out well, and plenty potent, but aren't very good on their own. Besides being slightly caustic because of what they are, they both seem to give a slightly chalky or smoky feel when vaped at low concentrations.
That brings me to my major concern with these: How much oil are they pulling out of the base material, and is the very small particulate matter actually burning on the coil? Inhaling oils is generally recognized as a bad idea, as is combusted organic matter. I have no idea if either of these is a real issue here, but I do remain wary of them. I would also be wary of sugars from fruits.
In any case, I do occasionally add a few drops of the two extracts that I still have to 10ml mixes for a hint of extra flavor, and a slight bite.
If you haven't seen it, a well-respected member here, who happens to be a chemist, has an interesting thread on tobacco flavor extraction that is an interesting read.
http://www.e-cigarette-forum.com/forum/liquid-extraction-tobacco/99774-vg-pipe-tobacco-essense.html
I've picked up quite a few things from reading the entire thing.