Depends on how or what device you use yours for all my squonkers I keep a designated flavor for each so.i don't have to clean them. If you are only using one squonker and wanting to try different flavors,then yes clean it out first. I am not sure how many times they can be cleaned without breaking down to a certain extent?
You can always pick up a 5 or 10 pack of spares to keep on hand for different flavors then you would not have to clean,well as much anyway.
You can always pick up a 5 or 10 pack of spares to keep on hand for different flavors then you would not have to clean,well as much anyway.