Sometimes it is Easier to concentrate on making a Creamy Vanilla 1st. Get it Perfected. Then SLOWLY add a Bit of tobacco Flavoring to it until the Blend is Right.
Vanilla can be a Tough Flavor to make. Because it can be Very Strong and Dominate other Flavors. I would Start with a Low percentage, 2 ~5% and work up.
Vanilla, in my mind, Also needs a Sweetener. And doesn't work in well if I use it Alone or Blended with one.
When I get my courage up I think I'll try a 4% vanilla (vanillin) and maybe 2% cotton candy? 30pg/70vg and no Nic wasted on initial flavor tests anymore.