Nicotine for sale?

Status
Not open for further replies.

Kendra

Super Member
ECF Veteran
Mar 21, 2009
806
0
Nashville
I guess we'll have to agree to disagree on this one. First, the whole point of contemplating my own personalized prescription is if, and only if, eliquid is no longer available in the US, even by importation of personal amounts directly by the consumer. Hopefully this is not going to occur, but it's a worst case failsafe idea.

Second, nicotine is already "approved" by the FDA - in patches, gum, lozenges and inhalers. Nicotine in a PG (or VG) solution is simply nicotine in a different carrier - no big stretch. Thus, I disagree that it would be so hard to find intelligent, thinking physicians who would be willing to provide an alternative to smoking for a patient via such a personalized prescription.

Third, that's the whole point of compounding pharmacies anyway - they make up compounds from otherwise legally available pharmaceutical raw materials, precisely in circumstances where the patient's needs can not be met by FDA approved and commercially available drugs. So long as they follow the federal regs governing compounding pharmacies, they are exempt from the FDA "new drug" approval process. (See, Medical Ctr Pharmacy vs. Mukasey (5th Cir. , July 18, 2008).

Medical Ctr Pharmacy vs. Mukasey - U.S. Court of Appeals for the 5th Cir. - July 18, 2008, Federal Circuits, Docket 06-51583 - vLex

So you see that following your reasoning to it's logical conclusion, there would be no compounding pharmacies, for no doctor would ever be so bold as to prescribe something not made available by the big Pharm gods and given the FDA blessing!
Oh, we don't disagree. .. I'm just speculating. I'd much rather you BE right and me BE wrong!

I hope we manage to keep this freely sold, but if not, I hope you're right and there will be some way to get it. :)
 

Kendra

Super Member
ECF Veteran
Mar 21, 2009
806
0
Nashville
I remember that thread and was just thinking about it today. .. thanks for finding it and posting it.

I think that this is even a better option. I think we'd be able to call them and ask them to send us the pure nicotine in a solution of pg or glyc. From what I read elsewhere on this forum (but don't remember who said it), someone said they've ordered poisonous drugs before for his "kitchen table" experiments and said it's as easy as a phone call to get.

I am just too much of a wuss to call and ask them to do that for me so far.
 

yvilla

Ultra Member
ECF Veteran
Verified Member
Nov 18, 2008
2,063
575
Rochester, NY
Oh, we don't disagree. .. I'm just speculating. I'd much rather you BE right and me BE wrong!

I hope we manage to keep this freely sold, but if not, I hope you're right and there will be some way to get it. :)

Well, on that we are in complete agreement! :)

Actually, as grim as it's looking with the FDA planning it's May 5th enforcement actions, I'm still really hopeful that individual consumer orders from China may always be available. That would be good for us, but not so good for all the thousands who may then never get started with ecigs. :(
 

Kendra

Super Member
ECF Veteran
Mar 21, 2009
806
0
Nashville
Well, on that we are in complete agreement! :)

Actually, as grim as it's looking with the FDA planning it's May 5th enforcement actions, I'm still really hopeful that individual consumer orders from China may always be available. That would be good for us, but not so good for all the thousands who may then never get started with ecigs. :(
I know! And, to top it off, it won't be something we'll be touting as wonderful anymore, since we'd be trying to keep our own use and "connection" under the radar. :(
 

Webby

Resting In Peace
ECF Veteran
Mar 31, 2009
796
15
USA
Perhaps we could hire a lab in the US to make liquid for us - legally? The proposed ban (which as I am seeing may or may not even happen) applies to the liquid nicotine.


Assuming we can still get cartridges (blanks) and hire a lab to produce them we'd be one step closer to the Lexus model (the reverse engineering of a mercedes) and making these here in the US.

On that note - anyone brought up the possibility of having an e-cig manufactured here in the good old US-of-A? With the current hoopla surrounding them it wouldn't be the best horse to bet on right now, but surely a US product would diffuse a lot of the connotation regarding Chinese imports being unsafe.

It would certainly put away QA issues - even if the things cost $250 a piece, they'd have a strong foothold as an apple pie product.
 

AGNES PEACOCK

Super Member
ECF Veteran
Mar 13, 2009
444
0
The Mother Lode, California
Yvilla:

I do believe you may have something here. I take BHRT (Bioidentical Hormone Replacement Therapy). My Bioidenticals are from a compounding pharmacy. Big Pharma would like it stopped as they have Premarin (synthetically made from a pregnant mares urine). Bioidenticals are made from yams and soy and the natural ingredients cannot be patented. Many, many people take them, the list is growing and includes celebreties. The FDA has several times tried to ban them. When a ban is mentioned there are marches, phone calls, etc... right up to the day of any decision making or voting. BHRT in invaluable in the lives of many women and men. They are not "approved by the FDA". I think the PV is just as important in the lives of many women and men.

I will speak to my prescribing doctor about this issue on my next visit and let you know what he says about the possibility of him prescribing such a nicotine product for me. And thank you for bringing this possibility to light, as it is definitely worth further research to me.
 
Last edited:

Rookie

Senior Member
Apr 19, 2009
74
8
Texas, USA
[quote=Webby;247512]Perhaps we could hire a lab in the US to make liquid for us - legally? The proposed ban (which as I am seeing may or may not even happen) applies to the liquid nicotine.


.On that note - anyone brought up the possibility of having an e-cig manufactured here in the good old US-of-A?

I don't know how to post the link but
check out the PURESMOKER thread
 

Vapor Pete

The Vapor Pope
ECF Veteran
Mar 14, 2009
2,847
2,134
Rochester, NY
Really? I like this one, actually. Soon maybe I'll change it. Didn't your mom teach you the whole, "if you don't have anything nice to say" thing? For instance, I haven't commented on your avatar.

:)

You are free to comment on mine... I know its scary, and Im not the best lookin dude in the world. If one goes to my profile, I have a pic of me not photo-shopped.
I didnt say your avi was hidious or something (that would not have been a nice thing to say, falling into what my Mom had taught me) I was only sayin I liked the real pic of ya better (an opinion). :D
My best,
-VP
 

Kendra

Super Member
ECF Veteran
Mar 21, 2009
806
0
Nashville
You are free to comment on mine... I know its scary, and Im not the best lookin dude in the world. If one goes to my profile, I have a pic of me not photo-shopped.
I didnt say your avi was hidious or something (that would not have been a nice thing to say, falling into what my Mom had taught me) I was only sayin I liked the real pic of ya better (an opinion). :D
My best,
-VP
Oh, I'm kidding. And, I did look at your profile. I like that picture on your profile much much better, too. You do look all mean and snarling here, but the one there is very very nice! ;)

Thanks, Pete. . . yes, we're still friends!
 

tokarev

Senior Member
ECF Veteran
Jan 25, 2009
297
473
Tennessee, USA
[quote=Webby;247512]Perhaps we could hire a lab in the US to make liquid for us - legally? The proposed ban (which as I am seeing may or may not even happen) applies to the liquid nicotine.


.On that note - anyone brought up the possibility of having an e-cig manufactured here in the good old US-of-A?

I don't know how to post the link but
check out the PURESMOKER thread

http://www.e-cigarette-forum.com/forum/puresmoker/15068-usa-manufactured-pv-cash-friends.html

We will still need a source of liquid, though.

TT33
 

Altmed

Full Member
Jul 20, 2010
38
4
S. California
Hi all!

I've worked in a lab and would not use any nicotine over say 30 or so mg/ml. Non-diluted nicotine is EXTREMELY toxic, and a very small amount can be deadly.

Anyone wanting to get into DIY refills should be familiar with Materials Safety Data Sheets (MSDS), and you may be required to keep them on the premises if making your own, but definitely if making it for sale.
It is important to be familiar with MSDS sheets, and have a notebook of them readily available, weather making your own or going into production.

DIYers should also have a good handle on doing the math (algebra) for dilutions. (say a solution with X %age of substance A, Y% solution of substance B & Z% solution of substance C)

There are premixed, unflavored vapor mix to add flavors to, which make it easy, FAR safer, and less math... say using 80% of a 24% solution with a 20% of a 0% nicotine solution.

Also be aware that when mixing chemicals, you need to understand how chemicals react and change each other. This may include some flavorings, which may change the effects of nicotine and other chemicals, so at least a basic chem class and at least a basic understanding of chemical reactions is as important as safety equipment. (goggles, lab coat, closed shoes, a wash facility or shower, gloves, proper containment receptacle, etc.)

I'd suggest getting an unflavored, pre-made vapor mix and adding already flavors to start.

Making your own mixes can be extremely fun and fairly easy, but trying to jump in with base chemicals e.g a high percentage nicotine, could be hazardous if handling precautions aren't followed.

With that said, have fun, but use caution & familiarize yourself with MSDS for the products you are using, which are available from the company you order from, and are usually available online.

Its just a matter of using any chemicals responsibly AND getting them from reliable sources...

Here's a VERY interesting story & a must read.. Some companies cut corners, such as in this "must read" article! Without access to a mess spec, reagents, etc. to test what you are getting, best to stick to very reliable, pharmaceutical &/or food grade chemical sources...

PLEASE READ...
Since I'm new, I can't post links, so Google "diethylene glycol sorbitol", then go to the about5th link called, "Diethylene Glycol and Sorbitol Mix Killed 45 - Panama Guide"

Food for thought!:2c:

-Altmed
 

grndzero

Senior Member
ECF Veteran
Feb 8, 2010
110
0
Tucson, AZ
I've been mixing my own juice for 3.5 months now. I just finished my first 1 oz bottle of 100mg/ml.

The only reason I chose to use to go with 100mg/ml instead of something lower is because I did a lot of research first and felt confident that I could deal with it. If the idea of really high levels of nic juice scare you, you can buy lower levels. 50, 36, and 25 are available. Understand though that the more diluted it is, the more you will have to use to get the nicotine level you want. To make a 5 ml bottle of juice (100 drops total) at 24 mg with 100 mg/ml nic juice it takes 24 drops. At 50 mg/ml it takes 48 drops, or over half the bottle. At 25 mg/ml juice 96 out of the 100 drops is nic juice.

DIYers should also have a good handle on doing the math (algebra) for dilutions. (say a solution with X %age of substance A, Y% solution of substance B & Z% solution of substance C)
eJuice Recipe Calculator This website is a godsend. Even though I can do the math by hand I always bring up this website every time I mix.

There are premixed, unflavored vapor mix to add flavors to, which make it easy, FAR safer, and less math... say using 80% of a 24% solution with a 20% of a 0% nicotine solution.
This is true, but understand that once a level is established you change it as soon as you add anything to it. If you buy a bottle of flavorless nic juice you will lower the nicotine level as soon as you add flavor. Some flavors need to be mixed at 10-15% to get the right level of flavor. You wil be diluting your nicotine level by that much.

Also be aware that when mixing chemicals, you need to understand how chemicals react and change each other. This may include some flavorings, which may change the effects of nicotine and other chemicals, so at least a basic chem class and at least a basic understanding of chemical reactions is as important as safety equipment. (goggles, lab coat, closed shoes, a wash facility or shower, gloves, proper containment receptacle, etc.)
There isn't a chemical reaction going on here, it's a mixture. The only thing you need to know is what percentage of flavor you need to get taste you desire then the ratios for the rest of the solution to get the desired nicotine level, pg/vg mix or anything else you want to add.

I'd suggest getting an unflavored, pre-made vapor mix and adding already flavors to start.
This is a great suggestion. Simple ratios are the best way to start. Mixing flavors. Understand though that with premixed juices you will always either be diluting the nicotine level or the flavor of the juice unless you are mixing flavors of equal nicotine strength.

Making your own mixes can be extremely fun and fairly easy, but trying to jump in with base chemicals e.g a high percentage nicotine, could be hazardous if handling precautions aren't followed.
As with all dangerous chemicals, guns, and generally dangerous stuff. Always pay attention to exactly what you're doing at all time. Get some latex gloves and absorbent pads if you need to. It's not really that daunting. Just make sure you store it properly and away from kids. It's been posted on the forum here many times. If you have small children in the house mixing may not be for you. At higher levels just a few drops on your skin can kill.

Its just a matter of using any chemicals responsibly AND getting them from reliable sources...
There are a few vendors on these forums that sell nicotine liquid for mixing. Their purity has been questioned and tested multiple times over, and probably will be continuously. That's about as reliable as you can get. It seems more trustworthy to me than ordering it from China.
 
Status
Not open for further replies.

Users who are viewing this thread