Here's a silly little tip I wanna share. CE2's can leak if they are turned upside down especially if you want to pre-fill extra CE2's and carry them with you. Hopefully you have tried other brands of cartos and have some of the rubber "condoms" laying around. On the regular size CE2 one large at one end and one smaller condom at the other end will seal off and cap the CE2's tightly. I pre-fill 2 or 3, throw them in a small ziplock bag and keep them in my pocket when I'm on the go. These last me all day and are not nearly as messy after you take off the condoms.