There's no such thing as a "real setup". There's only setups that work for you and those that don't.
If you're happy with what you have, don't go looking for something better. You'll likely just end up throwing away money.
If you're not happy with something, post what you're not happy with and someone will likely be able to advise you on how to address it.
For example, you said you're worried about running cartos dry and are always refilling them. In that case, a tank or a clearomizer would be a good idea so you can see how much juice you have. But there are potential downsides with them as well such as thickening juice, leakage, difficult refills, cracking, poor wicking etc.
If you just want to test out options, I'd go with one of the lavatubes (Mvari, Knight Rider, etc). They'll let you try different carts, clearomizers & attys at many different voltages so you can figure out what you like best and you can find them pretty easily for $50-70 with everything you need to get started. Once you dial in what you like, you can likely find a setup that specializes in delivering exactly what you want from a PV.
If you're happy with what you have, don't go looking for something better. You'll likely just end up throwing away money.
If you're not happy with something, post what you're not happy with and someone will likely be able to advise you on how to address it.
For example, you said you're worried about running cartos dry and are always refilling them. In that case, a tank or a clearomizer would be a good idea so you can see how much juice you have. But there are potential downsides with them as well such as thickening juice, leakage, difficult refills, cracking, poor wicking etc.
If you just want to test out options, I'd go with one of the lavatubes (Mvari, Knight Rider, etc). They'll let you try different carts, clearomizers & attys at many different voltages so you can figure out what you like best and you can find them pretty easily for $50-70 with everything you need to get started. Once you dial in what you like, you can likely find a setup that specializes in delivering exactly what you want from a PV.