I posted a thread similar to this, but specifically about having strange dreams when vaping too much before bed. First off, part of it may be the lack of cigs. Second, it's nicotine for sure (at first it's relaxing, then your mind kicks in and can keep you awake) In my case (the weird dreams) it turns out it was a combination of alcohol and nicotine. Basically, just try to vape a lower nic juice before bed (that way you still enjoy the other pleasures of vaping) I'm low budget, but ideally would like to have at least three tanks with different nic level juices: high nic for morning, medium for all day, and low for late evening. Currently vaping 12 mg juice (started with 18mg when I quit cigs) Don't plan on reducing that except switching to 6 mg before bed. If you have to (ocassionally) good ol NyQuil helps, but just like benadryl, don't use it too often. Eating something (or the warm milk thing) helps too, but if it's spicy, then here come the crazy dreams again.