Battery University will teach, but basically think of it like a car. If the engine is rated for 5000 rpm, you might be able to get it to 8000, or it might explode. The more you do it, the more likely it is to detonate.
The tool is easy - put in what you know (battery voltage, max discharge in 'ma') and hit calculate, it will tell you the rest. (In that case, it will tell you how many ohms your head has to be to be safe.)
You want to be much lower than the rating if you are using more than 3.7V, since the voltage increase is not especially efficient.
For example,
(PDF) this battery lists a 20A max discharge and 3.8V nominal voltage. So if you feed the converter "3.8V" and "20A" it says you would need a 0.2ohm head to run it at max. Totally safe for ecigs. (Anything higher than 0.2 will be lower amps. You can clear the amps field and tell it 2.5ohms and it will tell you 1.5 amps, much less than the listed-max of 20.)
(ETA: Also, I'd take the time to learn but then again, I'm a fan of my face.. This isn't a standard consumer device where someone else did all the work for you..)