Has she just ceased use of cigarettes? This symptom of chest tightness is a common symptom of nicotine withdrawal. Coupled with the fact that most e-cig users are getting less nicotine than when they smoked (can well be as little as 1/10 the amount, puff for puff), chest tightness on first starting
vaping/stopping smoking is not at all uncommon.
Here are a few links documenting the above:
"Chest tightness is normal, temporary and should not last for more than a few days. Aside from arising from the tension and stress associated with early withdrawal, it can be a component of normal dependency recovery blues (the emotional loss) or associated with the early cleansing, coughing and lung healing. Any tension or depression induced tightness or muscle stiffness may benefit form relaxation exercises, a warm shower, slow deliberate breathing or moderate exercise. Fluid or ice water may help with minor discomfort associated with tar and mucus removal or irritation due to coughing. Keep in mind that your lungs need moisture to help with healing and flushing".
WhyQuit - Nicotine Withdrawal and Recovery Symptoms
"Tightness in the chest
It is probably due to tension created by the body’s need for nicotine; may be caused by sore muscles from coughing. Part of the recovery process may be the lung’s attempt to remove mucus and tar. The normal mucus transport system will start to reactivate itself, which can initially cause coughing. It will last a few days. Deep breathing and relaxation techniques. Be patient; wait it out! Your body wants to return to normal".
Common Withdrawal Symptoms After You Quit Smoking - QuitSmokingSupport.com
Nicotine per cigarette puff - .1 mg
Nicotine per e-cig puff - .01 mg (I think this was with 16mg/ml or 1.6 strength liquid)
Ecigarette mist harmless, inhaled or exhaled