Virginia tobacco maker seeks new FDA designation - News Article

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Vocalek

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The story has been picked up by the AP News Service. This was one of the top sources when I googled the title.

Virginia Tobacco Maker Seeks New FDA Designation - ABC News

This is a good thing. Star Scientific is pushing the FDA to get cracking at setting up standards for Modified Risk tobacco products, as specified in the tobacco Act. In fact, tomorrow I am making a 5 minute presentation to the IOM Scientific Committee for on Scientific Standards for Studies on Reduced Risk tobacco Products. Bill Godshall will also be presenting. We are urging the Committee to establish standards that will fast-track products that already have a large body of research supporting comparative safety (e.g., snus) as "Modified Risk" and to consider any product that contains fewer toxins and carcinogens than cigarette smoke to be at a minimum "Reduced Risk."
 
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ScottinSoCal

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Is it just my natural paranoia, or is there something funny about the wording here:
Star Scientific says the tobacco contains 90 percent to 99 percent less tobacco-specific carcinogens than others currently available on the market.

Why not just "90 percent to 99 percent less carcinogens"? Or is there something that's not being said here?
 

Vocalek

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Is it just my natural paranoia, or is there something funny about the wording here:


Why not just "90 percent to 99 percent less carcinogens"? Or is there something that's not being said here?

Yup, it's your natural paranoia. Nearly all the carcinogens in tobacco come from "Tobacco-Specific Nitrosamines" that occur naturally in tobacco. Believe me, tobacco companies are not adding carcinogens in a nasty plot to kill off their customer base. In Sweden, they came up with a way of processing the tobacco to reduce those TSNAs. Swedes who use snus have no increased risks of mouth cancers over non-tobacco users. They have double the risk of pancreatic cancer, but we are talking about increasing from 4 to 8 per 10,000. The numbers are so small that this could be a statistical blip rather than a true risk increase. Smokers have higher rates of all cancers because burning tobacco creates 4,000 new chemicals, some of which are carcinogenic.

I don't know any of the details on how Star Scientific achieved this reduction. It might be a combination of breeding plants with lower TSNAs and processing that also reduces TSNAs. This is only a guess.
 

kristin

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Actually, the statistic on pancreatic cancer is questionable, as well.

Tobacco Truth: New Study: Smokeless Tobacco is NOT Associated with Pancreatic Cancer

With only 130 pancreatic cancer cases among ever smokeless tobacco users, the odds ratio (OR) is 0.98 (95% Confidence Interval, CI = 0.75 – 1.27). Twenty-three cases among exclusive users of smokeless tobacco produced an OR of 0.62 (CI = 0.37 – 1.04), which was almost significant for a PROTECTIVE EFFECT. Smokeless users who were also cigarette smokers had an OR of 1.36, which was not statistically significant (CI = 0.94 – 1.96) but confirms other studies that showed higher pancreatic cancer risks for smokers.

(The odds ratio is the measure used for case-control studies. Its interpretation is similar to that used for relative risks, which was discussed in this post.)

The importance of this study is hard to overestimate. First, it provides additional evidence that smokeless tobacco users are not at risk for pancreatic cancer. More importantly, it directly addresses a persistent question about the integrity of previous studies.
 
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Stubby

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I was just going to add that link Kristin but you beat me to it.

The link to pancreatic cancer and smokeless has been under question for some time. It only showed up in a few studies and those where questioned as to how rigidly controlled they where for other risk factors. All the newer studies are showing essentially no increased risk.
 

kristin

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There is plenty of independent research (non-tobacco funded) to back up the claim that smokeless tobacco does not significantly increase the risk of cancer. Tobacoo-specific nitrosamines or otherwise.

That's such a relief - they used to add carcinogens in a nasty plot to addict their customer base - I guess they learned?

Hmmm. I'm not feeling comforted.
 

Vocalek

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That's such a relief - they used to add carcinogens in a nasty plot to addict their customer base - I guess they learned?

Hmmm. I'm not feeling comforted.

Tobacco already has potential carcinogens that occur naturally in the plant (Tobacco-specific Nitrosamines -- aka TSNAs). But none of those potential carcinogens is addictive.

The addictiive chemicals that occur naturally in tobacco include nicotine and MAOIs, an type of antidepressant. Neither of these causes cancer.

I have never heard of a carcinogen that is addictive.
 

Petrodus

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A little off topic... However, it appears the government
has been listening to the tobacco industry's concerns

Tobacco seen as a potential bio-fuel

No worry here about secondhand smoke for commuters
stuck in traffic. The tobacco wouldn’t be burned to power
vehicles, merely used to extract its oils and sugars

Article: Click Here
 
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