WTA e-liquids

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rolygate

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This is a take-out from a thread in Media News where JF Etter's latest study is discussed. It started to go OT with a discussion of WTAs etc, so that is being continued here.

Tetsab said:
I am very keen to give WTA a try whenever this becomes possible as I'm quite conscious that as I approach my 3rd year anniversary as a vaper I believe quite strongly I am now consuming more nicotine than I ever did as a smoker. I vary quite a lot but on the 'bad days' when I'm possibly going through 5-7ml of liquid tend to believe that is simply my brain's refusal to accept that no matter how much I vape it still isn't going to satisfy the desire for what is not present in the vapour.

I am most intrigued by the way that you describe being able to vape WTA pretty much at will, without seeming to trigger the craving desire to continue doing so. Much of my trepidation at sticking my toe into the WTA waters (as it were), is bound up with a nagging concern about moving BACK towards tobacco. This isn't a result of concern about anyone's particular production methods or standards because compared to the damage which smoking was undeniably doing to me, this is essentially a non-issue for me. I've been more concerned about the possibility that WTA components might be involved as reinforcers in the addiction scenario. The experience you have described mitigates my hesitancy about this to some degree. Very interesting, and thankyou once again.

I think it is inevitable that WTA inclusion in e-liquids becomes more prevalent. There are certain pros and cons to this, so it will certainly generate a great deal of debate.

The pros:
- Will allow an e-cigarette to better replicate tobacco smoking, as more of the ingredients are included.
- Will allow e-cigarettes to totally replace dual-use of Snus and e-cigarettes. As a full tobacco substitute, the e-cig with a WTA-inclusive refill will do the job of an e-cig with a standard refill + Snus.
- The ~10% of ex-smokers who cannot do without WTAs will have a 100% e-cig route to switching instead of needing Snus as well.
- An e-liquid with a full tobacco alkaloid profile is more likely to provide better life-enhancing functionality for those with a proven deficiency after cessation of tobacco smoking than one with nicotine alone.

The cons:
- Current WTA e-liquid manufacturing quality controls do not appear to allow for full analysis and evaluation of the entire ingredient list.
- With current manufacturing standards it is impossible to state that WTA inclusion will not also bring across unwanted carcinogens.
- There is a possibility, and perhaps a probability, that WTA inclusion equals greater potential for dependence for some (but not all) users.

I speak as an extended time period user of WTA liquids who used them for 6 months during the switching process, and then quit them with no problem. So, for me at least, they were necessary in order to do the job properly, and then easy to remove from the consumption profile.

I don't see a problem with extended or even permanent use of WTAs - as long as strict manufacturing quality controls are in place. As a minimum this would include a full GC-MS analysis of the finished retail product being published regularly. Until that time I would understand if people see WTAs as an alternative with more risk than pure pharma-grade nicotine-only liquids. However, as compared with smoking, the risk is most likely so far down the scale as to be insignificant.

My personal opinion - and I must emphasise that it is purely personal - is that vaping an unflavoured nic base, where the user tests various products to ensure that the least problematic base material format is used, has a risk of about 10,000 times less than smoking. Using non-pharma grades of carrier (PG, VG), adding flavourings, and adding anything else such as WTA (only because they might bring along with them some unwanted materials) has to increase the risk.

By choosing your price point and your added inclusions, you determine your own risk level. I think that is entirely appropriate, since any way of converting away from tobacco cigarettes is going to reduce your risk by several orders of magnitude, and any way you can manage that has to be good - whatever the cheap and nasty cocktail you choose to vape.

As you can see I am entirely in favour of people buying the highest quality refills they can, which would include those that start out being made from the most expensive ingredients and finished in the best laboratory manufacturing facilities, and then having the finished retail product extensively tested and the results published. But that's an individual's choice entirely. You pays your money and takes your choice.

I feel it is a ridiculous situation for the government to be involved in regulating and testing materials that, however bad they are, cannot possibly be any less than 100 times safer than smoking. But it is fair to say that quality controls are not where they should be, as yet. It is way past the time when the trade needed to do something about this.
 

mooreted

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I know practically nothing about WTA. My only thought is: vaping is already working for me, do I really need more additives? Nicotine is very well researched whereas WTA is not. I probably wont jump on the bandwagon until some distant future when it's been thoroughly tested. I thought about it, but think I'll pass for now.
 

rolygate

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Mooreted, if you don't need it - then you don't need it.

Maybe 10% of people can't make the switch to e-cigs successfully as they still experience strong cravings, after the time period by which most find those cravings have ceased. For most of those individuals, adding Snus or WTAs does the trick. These extra alkaloids include anabasine, anabatine, nornicotine and myosmine. One or more has been used both in NRTs and for therapeutic applications such as reducing inflammation in arthritis. Snus contains them, which is why they supply the 'missing' element in tobacco that some e-cig users find problematic.

Extracting them from tobacco is more problematic than extracting nicotine, which is present in much larger quantities. The main issue is that some carcinogens may accompany them.

For one reason or another it's probably best to avoid them if you don't need them.
 

kinabaloo

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'Current manufacturing standards' aside (as I know nothing of these), there is no reason why WTA (just alkaloids) could not be as carcinogen free as a nicotine-only extract; the alkaloid nicotine is, after all, 95% of what WTA is. The process would most likely be the same up the WTA is extracted and is far far pure than steeping some tobacco in VG.

WTA is effective for those that need alkaloids bedides nicotine precisely because it duplicates the 'addiction' those people had. One would have to surmise that others were 'addicted' only to the nicotine; so no big difference here, and even if that 'addictiveness' is somewhat greater for those who need WTA to be off smoking, what of it is the thing one is addicted to is orders of magnitude safer? Such points obscure the benefits WTA could bring to millions.

If the fallacy that smoking = nicotine was true, there'd be no e-cigs because patches would do the trick for nearly everyone. E-cigs add the hand-mouth thing and the visible exhale, but still dont work for many people. The smoking = nicotine mistake has cost us years in progress.
+++

Noone is trying to 'add' anything to standard e-liquids; it's about having a choice, just as one could choose, say, snus. WTA is the truer combustion and carcinogen-free vapibg liquid, while current standard e-liquid is a cut-down / light version which only works for some people.
 
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kinabaloo

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Mooreted, if you don't need it - then you don't need it.

Maybe 10% of people can't make the switch to e-cigs successfully as they still experience strong cravings, after the time period by which most find those cravings have ceased. For most of those individuals, adding Snus or WTAs does the trick. These extra alkaloids include anabasine, anabatine, nornicotine and myosmine. One or more has been used both in NRTs and for therapeutic applications such as reducing inflammation in arthritis. Snus contains them, which is why they supply the 'missing' element in tobacco that some e-cig users find problematic.

Extracting them from tobacco is more problematic than extracting nicotine, which is present in much larger quantities. The main issue is that some carcinogens may accompany them.

For one reason or another it's probably best to avoid them if you don't need them.

I'd put your 10% figure at closer to 50%. We just don't hear much from the other 50%, they just fade away. Ever wondered why e-cigs are not the runaway success they should be? This forum is no busier now than 2 years ago. Quite a few sellers have closed down. I think you're seriously underestimating the need; just nicotine is not what hooked many people and so won't work as a viable alternative for them.

Extracting WTA is NOT more problematic; nicotine is an alkaloid same as the others in WTA. Extracting all the alkaloids without the other stuff is the easier part; extracting just the nicotine is the 'problematic part', if any. But clearly that's not difficult for a lab. WTA can be extracted easily and purely; it's a step to just nicotine after all. There's no reason why any carcinogens would be in WTA, they are not alkaloids so will not be selected; at the least, in no more than the case with just nicotine. The purification (selection of just alkaloids) can be repeated as often as required to achieve any level of purity; it's really not an issue.
 
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