For me, %DW suggests the % of distilled water in the final product, not strictly in relation to VG. So if you had a 30%PG mix, there would be no need for distilled water at all imo, as any distilled water added at this point makes the juice runny, easily flooded, and moots the point of higher VG mixing.
A simple rule of thumb would be to not let your VG% ever exceed 85%. This means that if the PG flavors and added PG amount to 15% or more, no DW is needed. You can modify this 'VG limit' to your liking. Some don't go past 80%, some go as high as 90-95% or even 100% if their flavorings are VG.
As for me, I've found that each recipe is unique, and thus experimentation is required. For example. some PG flavorings are runnier than others, and the same is true for VG flavorings. I've found Hangsen flavorings to be thicker (more viscous) than DIYFS's PG-free flavorings. This is accounted for in %DW. So lets say I was using 10% of a DIYFS VG flavor and 10% of a Hangsen flavor in different recipes. For the Hangsen, I would probably add 7% DW, whereas I would only add 5% to the DIYFS recipe.
Water dilutes VG more severely than PG, and alcohol more severely than water. So by adding 10%DW to the mix, it is equivalent of diluting the mix with something like 20%PG to me. This should be kept in mind, as many try to simply substitute their PG with DW and end up with a crackly, runny mix that over-dilutes their flavorings. I've found, through experimentation, that not alot of DW water is needed when the flavorings used are PG. I do not have a VG limit or a rule of thumb that I follow, but I've yet to find myself adding more than 8% DW to a flavored mix. When it's just unflavored VG nic/VG, I add 10% DW to thin it perfectly, so there would never be a reason to add that much or more water to a mix that has PG flavorings in it.