Accidentally Sleeping In E-Juice??

[QcVaper]

First of all i'm sorry but this just sounded hilarious to me
Second of all don't be sorry for something you can't control not your fault and no one here is an idiot it's a learning experience if anything. I've heard somewhere though that nicotine can be absorbed through the skin so that could be why you feel a bit weird. Usually whenever i change my cotton on my Rdas i wash my hands afterwards to remove any juice residue otherwise it's not very pleasant specially with 6mg.

 

[Zutankhamun]

I wash my hands because I’m not keen on juicy smelly fingers!
In the same way that some children have grubby little fingers I don’t want to be an adult in the same position!

I don’t wash my hands for fear of nic overdose when changing cotton

It’s only been a concern once and that was when I spilt 72% nic all over my hands when I was diy juicing. I only washed my hands with soap and water and all is well...

For now

I heard that nicotine slowly builds up over the years and before you know it. That’s the end.

Stay safe people

 

[r77r7r]

I've a question. Why is the OP's exposure different than wearing nic patches? I know someone that gets a buzz off of a single 14mg. Perhaps most of the bottle soaked right into the mattress. How much total nic in the full bottle? 180mg? I know some folks sub ohm near that much.

 

[Zutankhamun]

i misread. Oops

 

[untar]

I've a question. Why is the OP's exposure different than wearing nic patches? I know someone that gets a buzz off of a single 14mg. Perhaps most of the bottle soaked right into the mattress. How much total nic in the full bottle? 180mg? I know some folks sub ohm near that much.

For a start, 6*60 is 360 and not 180, so the total content was about 360mg. When talking about poisoning the amount you get into your bloodstream all at the same time is critical. While it may be true that you can consume 180mg of nicotine by e.g. vaping 30ml of 6mg juice that wouldn't even be remotely comparable to putting the same amount evenly all over your skin. It takes time to vape those 30ml, by the time you're half through that the nicotine in your blood will be at least partly metabolized, which means the concentration peaked and won't get significantly higher. With the liquid on the skin you absorb almost all at once in a very short time, leading to a far higher concentration in your blood stream.
If those folks subohm I suspect they use 3mg/ml liquid so the difference would be even more pronounced.

Nicotine patches also release their nic over time and not all at once.

 

[lil_buddy]

For a start, 6*60 is 360 and not 180, so the total content was about 360mg. When talking about poisoning the amount you get into your bloodstream all at the same time is critical. While it may be true that you can consume 180mg of nicotine by e.g. vaping 30ml of 6mg juice that wouldn't even be remotely comparable to putting the same amount evenly all over your skin. It takes time to vape those 30ml, by the time you're half through that the nicotine in your blood will be at least partly metabolized, which means the concentration peaked and won't get significantly higher. With the liquid on the skin you absorb almost all at once in a very short time, leading to a far higher concentration in your blood stream.
If those folks subohm I suspect they use 3mg/ml liquid so the difference would be even more pronounced.

Nicotine patches also release their nic over time and not all at once.

Please provide a source for this claim: "With the liquid on the skin you absorb almost all at once in a very short time, leading to a far higher concentration in your blood stream."

 

[lil_buddy]

"What was found:

It took 2 hours for any nicotine to transfer through the skin, and at an average rate of 4.82 (±1.05) µg/cm2/h (micrograms per cubic centimetre of exposed skin, per hour), or in the milligrams we are more accustomed to, 0.00482mg/cm2/h. The area of half of the human palm is considered to be between 90 and 100 cm2 so contamination of this area would give (assuming 100cm2 area) 0.482mg/hour.
"
New research into nicotine absorption through the skin | ECITA - Electronic Cigarette Industry Trade Association

 

[untar]

@lil_buddy good that you picked up on that, it made me look back into a study on nicotine absorption I read a while ago and I seem to have grossly misread/misremembered something (milligrams instead of micrograms). So the absorption is about 1000 times worse (=lower) than I thought. Here's my source
Transdermal nicotine absorption handling e-cigarette refill liquids. - PubMed - NCBI
Here's a source for nicotine in blood plasma through vaping
Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices

It was also not correct to say it would be absorbed faster, it takes about 2h to get through the skin, which then acts as a buffer and releases the nicotine into the body with the rate mentioned in the study.
I'd have to take a while and do some math now before trying to correct my previous post.

Edit: well, seems I'm too slow, didn't see your 2nd response before typing this

 

[jfcooley]

Eh, I've slept in worse.

 

[Beamslider]

I doubt seriously if 60 ml of 6 mg nic is enough on the skin to give you nic sickness to any serious degree. That is 360 mg total and there is no way that you absorbed anywhere near all of it.

You do need to change those bed linens though

 

[untar]

I'm sorry, this gets more complicated quickly as every "delivery system" peaks at different times and the difference at which humans metabolize nicotine seems to be pretty damn big.
Nicotine Chemistry, Metabolism, Kinetics and Biomarkers
What's more, nicotine permeability of the skin is dependant on the nic concentration
http://annhyg.oxfordjournals.org/content/43/6/405.full.pdf+html
The concentration used in the study of transdermal nicotine absorption was only 0.8mg/ml (see my link, no mention of the concentration in the ecig industry article), how the rate changes when we go up to 6 or 8mg/ml is anyones guess. There's no data, even for the water solution experiment, for concentrations between 0.1 and 1% nic concentration (which would be close to 1-10mg/ml, a pretty common range novadays).

Answering rr77r7r question will take more than a few hours, more like a project for a week or two, or maybe a bachelor degree

 

[lil_buddy]

no mention of the concentration in the ecig industry article

"
The level of nicotine was reported as 8mg/g, rather than the more usual 8mg/ml, and it is not clear if the slight difference between these two values (e-liquid has a slightly higher density than water, so an 8mg/ml solution would actually be slightly lower in mg/g) was considered. More alarmingly, this level was inaccurately reported as 8%, whereas it is actually 0.8%. Fortunately, all the calculations were conducted in w/w units so this mistake doesn’t appear to have affected the results, but it is surprising that this was not picked up during peer review.
"
New research into nicotine absorption through the skin | ECITA - Electronic Cigarette Industry Trade Association

 

[untar]

True, but if you look into the sources it says "0.8mg/ml". So while I butterfingered right over that passage at the end, 0.8mg/ml is still the correct dose they used. It's the same in the sciencedirect link on their site as it is in my link to ncbi.
"Donor chambers of eight Franz diffusion cells were filled with 1 mL of 0.8 mg/mL nicotine e-liquid for 24 h."
Edit: maybe there is a difference in the full text version but that's behind a paywall, as usual

 

[BrotherBob]

60 ML, 6 MG.

Welcome and glad you joined.
Hope you are feeling ok with this strength exposure, probably are by now. If you ever do DIY, you may want to keep the serious high grade nicotine in a combination lock box. Might get two of them and use one for e-liquid by the bed.