It's all about what works for you. Started with some 24mg, was way too much for me, turned to 12mg, then quickly to 10mg. Now I feel (some, occasional) anxiety when I use 12mg (it's all psychological). I really wanna go to 0 nic juice, but I need the throat hit. Smoked for twenty years, blood clot in my lungs twice but still couldn't quit, yet I believe I could easily give up nic - as long as I can get the TH. But, again, it's all about what works for you