Alrighty, I only made it through 8 pages, so some of my points may have already been addressed by others, but as a small business person myself this thread touched a nerve for me, so here's my take on this....
Juice prices in general seem to me to have come down over time, it used to cost more to get quality US mixed juices than it does now. I'm basing that on the assumption that the companies I haven't tried that are purported to mix quality juices do so, as I have largely stuck with the vendors I found many moons ago that made flavors I like.
There's a portion of the vaping community that's constantly bemoaning the lack of quality control and transparency in juice vendors out of one side of their mouth and then .....ing about anything over so much per ml out of the other side of their mouth.
In the meantime juice companies have invested an incredible amount of time and effort, not to mention significant and ongoing financial investments into starting a company that could be flushed down the toilet by the FDA at any given moment.
And yes, even a juice with high quality ingredients can surely be mixed for 12 cents a ml or whatever random amount someone else noted, but it never seems to occur to some people that the labor to make that juice must surely be paid for. Not to mention the time spent sourcing the ingredients, researching them for potentially harmful ingredients, receiving them and stocking them into an aseptic environment, testing nic level of the bases, creating and implementing quality control systems, printing and labeling bottles, printing invoices and packing slips, packing orders, keeping accurate records including accounting..... Those are just some things off the top of my head.
And we didn't even get into the facility, facility maintenance, equipment (have you ever looked at the price of lab equipment?), insurance....again just scratching the surface of the list of overhead costs.
Not to mention I think we can probably all agree it would be great if more companies got labs to at least occasionally test their finished products, and I can't imagine that's cheap.
And of course, heaven forbid there be some net profit nestled in there somewhere for all that hard work and risk.
I can only assume that the companies charging 50 cents a ml or less are operating on such a scale and have found such efficient ways to do things that they are indeed doing the things that most seem to want: operating a juice making lab with aseptic conditions to make juices that are as safe as possible. On the other hand, as just a small business person imagining what it must take to do that I find it difficult to conceive of how they're accomplishing that.
And just on a completely anecdotal note it boggles my mind that some people who used to spend $5 a pack and up on cigs will piss and moan about an $18 30 ml bottle of juice.