The biggest problem with very low nicotine cigarettes is that those who advocate/research/tout the products (as a way to reduce the addictiveness of cigarettes) want the FDA to impose mandatory standards to require ALL cigarettes to sharply reduce their nicotine levels.
A decade ago, Vector (formerly Liggett)
tobacco company test marketed Quest cigarettes (that contained very low nicotine levels, as a strategy for smokers to wean themselves off nicotine) in seven states, but Liggett never marketed Quest nationwide and halted their test market because nobody bought them (i.e. smokers didn't like them or want them).
Unfortunately,
tobacco control researchers don't understand that markets are created and sustained by consumers, as they myopically believe that markets are created and sustained by government regulators.
After I informed the low nicotine cigarette advocates that smokers won't
buy very low nicotine cigarettes (even if FDA mandates them), their response was basically "that would be even better for public health".
This demonstrates that most/all very low nicotine cigarette advocates are just prohibitionists, and that FDA standards to mandate very low nicotine cigarettes is nothing more than backdoor prohibition of cigarettes.
Similarly, the proposed EU TPD would mandate very low nicotine levels (i.e. 2mg) in all e-cigarettes because those who proposed it knew that limiting nicotine to 2mg in e-cigarettes would be the same as a ban on all e-cigarettes (but of course they called it a regulation).