No Debate or Argument from Me as I have neither the time nor the desire to engage anyone in inane irrelevant Futility Exercises.
However, since the OP asked and All Opinions and Experiences are equally as Valid and Invalid as another;
I drip/RDA and load my RTA's with both 50/50 & 70/30 mixes in both 18 & 16mg Nic on both Variable and Mech Mods depending on what I choose to "flip my switch" at the time. Dripping Mech Sauce Blue Tentacle in 70/30 18 Nic on a 13/9 RDA & Hollowpoint Mech in between typing with my Index Fingers

Oh the depths of Hedonism and Reckless Protocol Abandonment some stoop to

Doesn't make it Right or Wrong, Good or Bad, Suggested or Not.
Just what "works" for me and has been for over 2 years. Your Opinions and Mileage may vary and that's Cool too.
Ain't no Cookie-Cutter "One-Size Fits All correct Answer. Depends solely on Device/Rig being used and Personal Preference
So (to actually answer the OP's Question), Can You? Absolutely!
Do/Should you Want/Need/Desire to? That's up to the Individual to decide for themselves.
All the best to you.
Enjoy & Vape-On!