Has giving up nicotine ever caused serious problems for you in any activities of daily living, such as job performance, driving a car, or getting along with others?
I can't answer the poll yet - I had two months nic free in the summer. No obvious cravings because chain vaping. Was pleased about this. But my immune system went to pieces:- viral kidney infection, dental abcesses, fungal scalp infection, cellulitis, swollen ankles, and worst of all, post viral fatigue syndrome, and I date the beginning of my (slow and ongoing) recovery from the day I went back to using some nic juice and a snus now and then.
Coincidence or cause? Dunno.
C.
The few times I've been off all nicotine ... you do not want me around.
I have a flash point near zero and lash out. Nicotine is my "balance". It stabilizes me, and the world can be dealt with. Without it, I'm deficient in something that keeps me on an even keel. Moody and angry would describe me without my e-vitamin.
Similar symptoms to what you describe Vocal. But this happened to me on reduced nicotine, not total abstinence.
I thought I'd try to cut my nic intake some time back. Before starting to use snus along with vaping I would use from 3 to over 4mls of 36mg a day. Started cutting the nic to 20 to 24mg and liquid usage went up, along with irritability!! Focus, concentration and memory dropped. After a bit over a month of this I went back to 36mg and by and large these complaints were gone within 24 hours.
Since augmenting with snus, I still vape 36mg, but rarely do I exceed 1.5ml in a day.
Did you resume the nic, Vocal?
C.
I can be very stubborn. I held out for six months, waiting for the promised "It will get better." Finally, I told the doctor that I had no choice but to start smoking again.
That was almost 20 years ago. At least I didn't go back to 2-1/2 packs a day.
Translation: Nicotine is a useful treatment for inflammatory diseases such as arthritis. Nicotine reduces inflammation.RESULTS: Clinical arthritis was exacerbated by vagotomy and ameliorated by oral nicotine administration. Moreover, oral nicotine inhibited bone degradation and reduced TNFalpha expression in synovial tissue. Both IP-injected nicotine and AR-R17779 ameliorated clinical arthritis and reduced synovial inflammation.
Pregnancy-induced hypertension (PIH), also known as preeclampsia, is one of the major causes of maternal and fetal death. While the precise cause of PIH is not known, aberrant cytokine production and placenta participation are considered to be important factors. Gestational cigarette smoking, which is widely accepted to be harmful to both the mother and fetus, is protective against PIH.
Stimulation of nicotinic acetylcholine receptors a... [Arthritis Rheum. 2009] - PubMed result
Translation: Nicotine is a useful treatment for inflammatory diseases such as arthritis. Nicotine reduces inflammation.
There are many diseases related to inflammation, including arthritis, fibromyalgia, and even vascular disease. Smoking appears to worsen vascular disease, but apparently it isn't the nicotine that causes the problem.
IMO: The swollen ankles (body retains fluid) is an inflammatory response, perhaps tied in with the high white blood cell count.
I'm told that when you are retaining fluid, the best thing to do is take in lots of fluid so your body stops responding as though you are about to die of thirst.
When I was pregnant with #1, I cut back to about 4 cigarettes a day. Toward the end of my pregnancy, I was retaining an enormous amount of fluid. My feet were so swollen I had to buy larger shoes. Doctors were watching for "Preeclampsia", but I never developed any high blood pressure. I lost 18 pounds in the first 24 hours after delivery. Fluid was coming out of me any way that it could, including through my pores and hair follicles.
I did not cut back smoking so drastically with #2, and did not develop the edema. Perhaps pure coincidence. Hard to say.
Oh, just found this article on PubMed, too.
Nicotine inhibits cytokine production by placenta ... [Mol Med. 2007 Nov-Dec] - PubMed result
So maybe it was NOT a coincidence. Hmmm....
NOTE: PubMed search was for "nicotine antiinflammatory"
...is capable of producing, altering, or releasing acetylcholine ("indirect-acting") or mimicking its behaviour at one or more of the body's acetylcholine receptor types ("direct-acting").
It was later developed by Janssen Pharmaceutica into an Alzheimer medication. In the US it has been sold as a dietary supplement for memory and dream support prior to being approved as a drug by the FDA.
The few times I've been off all nicotine ... you do not want me around.
I have a flash point near zero and lash out. Nicotine is my "balance". It stabilizes me, and the world can be dealt with. Without it, I'm deficient in something that keeps me on an even keel. Moody and angry would describe me without my e-vitamin.