The flavors and the vapor coating your throat, along with the nicotine will make you dry. It is always good to drink water, and it is even more so important to do when vaping. If you feel the effects of too much nicotine (sweating, headache, shaking, etc.), chugging cold water helps bring you back to normal. I work in a voice over studio, so I am talking and vaping all day-I am pounding water as often as I am vaping...which is to say, often.