VV device eliminates the need to use LR attys. LR attys burn out faster than SR or HR attys.
With a VV, you can adjust to the wattages that lie between what you would achieve by changing resistance. In effect, you can get the same vape as you might get with a 3.69ohm atty, if it existed.
Higher resistance with higher voltage, allows finer increments. A 0.1V change from 4.75V on a 2.8ohm changes the wattage less than the same 0.1V change on a 3.5V device with a 1.5ohm resistance.
Most batteries on a fixed voltage device will begin providing less voltage as they become drained. As your battery drains, you can increase the voltage to compensate.
If you have a carto full of your favorite juice, you may like it warmer in the morning and cooler at night. With a VV, you don't have to load two different cartos with the same juice.
There are wattages that provide the optimum vape with any given juice and under any given circumstances, that you cannot achieve by mixing and matching batteries and different resistance cartomizers.
I have a juice that's perfect at 8 watts. I have a fixed volt device. When it's providing 4.2V, right off the charger, I need a 2.2ohm carto. When the voltage falls to 3.7, I need a 1.7ohm carto. That's a tall order. With a VV, I can level off my 3ohm carto to 4.9V and nail it.
Those are a few off the top of my head. Hope they make sense.