Half life of nicotine vs Caffeine

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MonkeyMonk

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Feb 17, 2009
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taz3cat it goes like this: 1/2, 1/4, 1/8, 1/16, 1/32... to infinity

I, too am finding 2 hours more frequently being cited for Nicotine half life.

Here is an interesting paragraph from the following link:
Google Answers: Nicotine and Cotinine tests
"Nicotine is cleared from the blood by liver enzymes that convert it to
its metabolite cotinine. Blood analysis showed that it took an average
of 152 minutes for half the injected nicotine to degrade in the blood
of the Chinese-Americans in this study. Nicotine's half-life in whites
and Latinos was 134 and 122 minutes, respectively. Slow metabolism of
nicotine draws out its effects, says Neal L. Benowitz, a clinical
pharmacologist at the University of California, San Francisco. He and
his colleagues report their work in the Jan. 16 Journal of the
National Cancer Institute.?
http://www.sciencenews.org/articles/20020119/fob6.asp"

SmokeHelp's Frequently Asked Questions
"How Long Can Nicotine Be Found in a Blood or Urine Test.
1 year assuming you are not working or living in the presence of second-hand smoke."

It is my understanding that cotinine is what is tested for when testing is done to determine if a person is a smoker. This link is about Cotinine:
FBR Cotinine Pamphlet
(It cites 7-10 days to reduce to that of a smoker. However, I have read that long term chain smokers might be able to be detected for up to 3 months or longer.)

Also, I posted this link in a different thread before. I do not know if the product works, but this is just an FYI that there are things like this out there:
Pass Nicotine Drug Test - Insurance Blood Drug Testing
 

MonkeyMonk

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Feb 17, 2009
687
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Stogie, alcohol is goverened by a different factor, the metabolism is linear not exponential.

And, long term use of alcohol affects the liver and hence the metabolism of alcohol.

For instance, I stopped drinking in 1997, I had 3 one day slips. I can tell you that just one mouthful of alcohol would effect me the way 2-3 drinks would affect someone else. Just one mouthful would give me the buzz and the woozieness. My body would not metabolize it as well as someone who never abused alcohol. I believe the answer would rest upon the health of the persons liver.

However, here is a link to the basic explaination of alcohol metabolism:
Blood alcohol (Steven B.
Harris, M.D.; Carey Gregory)

"...No, what is meant is that the % alcohol in your blood goes down by
015% per hour, or something like that.
Which does amount to a
constant rate. As somebody pointed out, at levels of alcohol which
drivers have to worry about, metabolism is zero order kinetic, which
means that the enzymes are saturated, and the rate of disappearance of
ethanol in the body is INDEPENDENT of concentration. Thus,
concentration falls off linearly, not exponentially. No half-life.


Steve Harris, M.D."

Alcohol Metabolism
(The article explains alcohol metabolism and the graph is from the article)
 

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