All good information above.
Here is my take on this, for whatever it is worth. All I will say is I have read up on it for myself extensively since 09 and would urge you to do the same so you can make your own informed (as existing data permits) judgement:
Get an analog and a piece of tissue paper.
Get your e-cig and a piece of tissue paper.
Use both for the same amount of puffs, blowing the smoke/vapor out through the tissue paper.
Compare the two tissue papers afterwards and you will have a your own answer of which is likely better or worse.
Can anyone guarantee vaping is 100% safe for everyone at any level of usage? NO.
Can anyone guarantee smoking is safe? NO.
Is the safest option to simply not do either? YES.
Is it reasonable given the data available to say that vaping is safer than smoking? IMHO YES. I feel somewhere around 95% safer is an educated guess.
Is most of your base liquid PG? PG is used in hospitals to deliver inhalable medications, so proven safe enough for that limited usage. Both however have been discussed above.
How many chemicals are in a cigarette? over 4,000 chemicals, including 43 known cancer-causing (carcinogenic) compounds and 400 other toxins. These cigarette ingredients include nicotine, tar, and carbon monoxide, as well as formaldehyde, ammonia, hydrogen cyanide, arsenic, and DDT.
How many chemicals are in your juice? You could vape pure VG, PG, just a combo of the 2 or add nicotine and flavorings. Is this less than 4000? YES.
Are there unsafe things in some brands of pre-made e-juice? YES.
Are there companies that make safer e-juice than the ones above? YES.
Can you easily make your own juice with just a few known safe (for now) ingredients? YES.
I use an 80/20 mix of VG/PG and a dash of menthol crystals for flavor as my "daily driver mix". I think this is FAR safer than analogs. I used to have nicotine in the mix also, but do not need/want it anymore. On occasion I will use a different flavoring.
Hope this helps, good luck!