How dangerous is 24mg e-juice on skin?

[designinme]

I have been vaping for about 3 weeks.. analog free for almost a week. Everything is going well.

When I vape, I use 24mg l e-juice... I thought about going higher to see if that helped my cravings, but so far I think I am good with the 24mg.

My concern is how harmful is getting the 24mg on the skin? I drip and at times have gotten a good amount in my mouth from overfilling the cart.. and other times I have dripped and spilled some out onto my fingers.

Is this considered quite dangerous to touch? I don't want to sound paranoid, but I read on here from another poster that 60mg e-juice, just one drop on the skin could kill you? Wouldn't that be the same as getting 3 drops of 24mg?

I just want to have a better idea of how much contact ( its not like I try to touch it ) but how much could really cause a serious problem if I touch. Hell I get it in my mouth often!

I was a two pack a day smoker.. isn't that about 2mg/cig x 20 packs = 80mg of Nic a day?

So if I vape 4 ML of 24mg e juice.. about the same nicotine level.. correct?

 

[Angela]

60mg of nicotine is technically enough to kill you, but, even at 60mg liquid you would need a full ml (approx 20 drops) to have 60mg of nicotine.

Then, of course, the suspension liquid (eg PG or VG) will inhibit the absorbtion through the skin as the nicotine will be held in the suspension for longer.

Don't panic about a drop or two of 24mg, but it is a good idea to wash your hands if you do get it on your fingers (each drop will only contain around 1.4mg of nicotine - ie 24/20=1.4) - especially if you have children or pets around, whose tolerance will obviously be much lower that yours.

I am very keen to make sure that people know about the dangers of nicotine, but don't think that we need to be panicing over handling e-liquid.

 

[beckah54]

I often get 24 mg juice on my fingers and occasionally, in my mouth. I keep a paper towel handy to wipe it off my fingers but I've never felt any ill effects from the liquid. Just use a little caution and you'll be fine.

 

[sbphotog]

I thought about going higher to see if that helped my cravings, but so far I think I am good with the 24mg.

Going higher will not help your cravings and will likely make you sick.

Your cravings are from the withdrawl of other chemicals that are in cigarettes that are not present in the nicotine juice. No matter how high you go in nic mg, you'll still have cravings to deal with when you completely stop analogs. You just have to let your body deal with it.

 

[umop apisdn]

Snus might help you out. Using it sparingly will help you get some of the chemicals (mostly MAOIs) that come from tobacco. It might be tobacco, but at least it isn't smoke.

 

[MaxUT]

I've gotten a couple drops of 48mg liquid in my mouth with no apparent ill effects beyond a stinging sensation which soon faded away.

Speaking of snus, I've experimented with using nicotine e-liquid as a kind of liquid snus.* Needs more development...

*Note to self: always carry enough batteries to get you through the work day.

 

[Slickstick]

No 24mg spilled on your hands will not kill you. I wash my hands though because I have ferrets.
30 helped my cravings.. 36 i can only vape half as much I get a nicotine buzz going and have to chill. I go back and forth 24 30 24 30

 

[Travis798]

Going higher will not help your cravings and will likely make you sick.

Your cravings are from the withdrawl of other chemicals that are in cigarettes that are not present in the nicotine juice. No matter how high you go in nic mg, you'll still have cravings to deal with when you completely stop analogs. You just have to let your body deal with it.

Going higher helped my cravings and didn't make me sick. I don't understand what some peoples problem seems to be with 36mg. Just because you didn't need it, doesn't mean that others don't need it.

 

[supertrkre2812]

I've had people tell me that they need to vape 48mg. It all depends on your own individual body, and only you know your own body and what it needs.
As far as getting 24 on you, I spilled some in my lap, i just got up, changed shorts, wet a wash cloth and wiped it off. Thats all, and i'm still alive.
I get a little liquid in my mouth all the time from overfilling my carts.
It tastes nasty, i just wipe my tongue on a paper towel and wipe the cart off and keep on vapin!!!

 

[Travis798]

I've had people tell me that they need to vape 48mg. It all depends on your own individual body, and only you know your own body and what it needs.
As far as getting 24 on you, I spilled some in my lap, i just got up, changed shorts, wet a wash cloth and wiped it off. Thats all, and i'm still alive.
I get a little liquid in my mouth all the time from overfilling my carts.
It tastes nasty, i just wipe my tongue on a paper towel and wipe the cart off and keep on vapin!!!

Okay so Friday I was drunk, and ended up with we'll say a fair amount of 36mg nic on my lips and in my mouth. I didn't worry about it too much, Just took another drink to wash it down. Of course it didn't hurt me as far as poison, but it did chap my lips pretty good and the inside of my mouth is still sore, but I'm alive.

Personally, I'm not THAT scared of this stuff. I could accidentally spill an entire 10ml bottle on me and I wouldn't panic. I would wash it off of course, but 1 drop of 60mg on your skin isn't going to kill you.

 

[TWISTED VICTOR]

Going higher helped my cravings and didn't make me sick. I don't understand what some peoples problem seems to be with 36mg. Just because you didn't need it, doesn't mean that others don't need it.

I started out with 24mg, then ended up with 52mg to satisfy the crave. Currently I'm a steady 36mg vaper, but often bump up to 48mg in times of trouble. Everybody's different.

 

[stormy1]

I have found using 35/36 in the morning helps, 18 or 24 is fine the rest of the day but doesn't have enough kick for in the morning.
I think the 36 will let me totally kick analogs because I am down to a 1/2 pack from 3 packs plus.
Everyone is different.

 

[markule]

Safety (MSDS) data for nicotine

LD50 is 50mg/kg. For me, about 100 kilos, that's 5000 mg, or 5 grams pure nicotine, or 100 mL of 50 mg/mL. For a 22 pound child, or 10 kilo, that's 500 mg, or 10 mL at 50 mg/mL. Ever try to drink 10 mL of this stuff? Or spill that much on yourself and let it soak a good long while? You'd be way sick first.

I don't know where these numbers come from, but similar ones are used elsewhere, indicating one drop will kill you. Just not true, based on the MSDS.

 

[olderthandirt]

Safety (MSDS) data for nicotine

LD50 is 50mg/kg. For me, about 100 kilos, that's 5000 mg, or 5 grams pure nicotine, or 100 mL of 50 mg/mL. For a 22 pound child, or 10 kilo, that's 500 mg, or 10 mL at 50 mg/mL. Ever try to drink 10 mL of this stuff? Or spill that much on yourself and let it soak a good long while? You'd be way sick first.

I don't know where these numbers come from, but similar ones are used elsewhere, indicating one drop will kill you. Just not true, based on the MSDS.

The numbers you are citing, 50mg/kg, are orally administered for a rat, or applied to the skin of a rabbit.

The oft used LD50 number on this forum for a human is a TOTAL of 60mg.
The only place I've been able to find this particular number is on the wikipedia page for nicotine. The source of that figure is cited but I've not had any success in locating the actual source.


PLEASE people. before you start posting numbers and "facts and figures" do EVERYONE A FAVOR and make some attempt at having a clue BEFORE YOU POST!

FFS

EDIT: One of the sources in the following post

 

[olderthandirt]

Nicotine (PIM)

7. TOXICOLOGY 7.1 Mode of Action Nicotine is an agonist at nicotinic receptors in the peripheral and central nervous system. In man, as in animals, nicotine has been shown to produce both behavioral stimulation and depression. Pharmacodynamic studies indicate a complex dose response relationship, due both to complexity of intrinsic pharmacological actions and to rapid development of tolerance.
7.2 Toxicity

7.2.1 Human data
7.2.1.1 Adults The mean lethal dose has been estimated to be 30 to 60 mg (0.5-1.0 mg/kg) (Gosselin, 1988).

7.2.1.2 Children The lethal dose is considered to be about 10 mg of nicotine (Arena, 1974).

7.2.2 Relevant animal data
Dog: oral LD50: 9.2 mg/kg
mouse: oral LD50: 3.3 mg/kg (RTECS, 1985-86)
rat: oral LD50: 50 mg/kg

And so you all know just what LD50 is:
Median lethal dose - Wikipedia, the free encyclopedia

 

[Lab]

I just got the 24 mg.. had cravings for a real cig for awhile until i smoked one could only take 3 drags of it.. and it tasted horrible

as far as spilling it.. I get the stuff on me all the time throughout the day.. i don't worry about it have spilled a lot worse chemicals on myself. besides patches are i think 24 mg and they stick on you for hours and do not kill ppl

 

[john doe]

just a couple small notes. pg actually helps the nicotine get past the skin barrier. itm is used in some topical medicines to transport the drug through the skin.
the patches are usually 7-14-21 mg but that's slow absorption over 18-24 hours and probably still isn't all used.
i'm not saying it's dangerous to get a few drops on or in you but as stated earlier as long as you clean up after a big spill you should be ok.

 

[Angela]

just a couple small notes. pg actually helps the nicotine get past the skin barrier. itm is used in some topical medicines to transport the drug through the skin.

That's interesting that you say that, as I've seen a qualified chemist state that the PG / VG solution would hold the nicotine molecules within the suspension and slow down absorbtion compared to pure nicotine alone.

 

[john doe]

possibly the nicotine alone passes the skin barrier faster than i thought however the use of pg to get other chemicals past the barrier is still true.

 

[NanoVapor]

Ive experimented with some very potent compounds lethal in the single digit microgram range (an amount you cannot even see with the naked eye would kill 10+ people) and TRIED to simulate such a fatal skin exposure to an ultra-high concentration aqeous (distilled water) solution (10mg/ml) several times (whilst having a pre-loaded syringe of the suitable receptor antagonist handy of course). I was never able to kill and save myself. I left copious amounts of the solution on my skin for 10+ minutes. Without suitable solvent carriers, the transdermal absorption rate was dismal (and keep in mind this is microgram lethal so very very few molecules even need to absorb).


Theres almost no way your going to be able to transdermally administer a fatal dose of nicotine without utilizing special carrier agents to do so.