How dangerous is 24mg e-juice on skin?

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Ive experimented with some very potent compounds lethal in the single digit microgram range (an amount you cannot even see with the naked eye would kill 10+ people) and TRIED to simulate such a fatal skin exposure to an ultra-high concentration aqeous (distilled water) solution (10mg/ml) several times (whilst having a pre-loaded syringe of the suitable receptor antagonist handy of course). I was never able to kill and save myself. I left copious amounts of the solution on my skin for 10+ minutes. Without suitable solvent carriers, the transdermal absorption rate was dismal (and keep in mind this is microgram lethal so very very few molecules even need to absorb).


Theres almost no way your going to be able to transdermally administer a fatal dose of nicotine without utilizing special carrier agents to do so.


Why the hell would you even attempt to do that?

Derek
 

Raven1

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Going higher will not help your cravings and will likely make you sick.

Your cravings are from the withdrawl of other chemicals that are in cigarettes that are not present in the nicotine juice. No matter how high you go in nic mg, you'll still have cravings to deal with when you completely stop analogs. You just have to let your body deal with it.

Don't I know it!! I'm still smoking about 7 analogues a day because I can't handle the withdrawal symptoms (trying to decrease by 1 every few days). I wouldn't suggest a higher nicotine level either - I tried that and it made me feel ill. vaping more made me feel ill too, so yes, you just have to deal with it, no matter how uncomfortable it is if you really want to quit. You might try some Valerian or other herbal anxiety remedy too.
 

JohnnyVapor

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The numbers you are citing, 50mg/kg, are orally administered for a rat, or applied to the skin of a rabbit.

The oft used LD50 number on this forum for a human is a TOTAL of 60mg.
The only place I've been able to find this particular number is on the wikipedia page for nicotine. The source of that figure is cited but I've not had any success in locating the actual source.


PLEASE people. before you start posting numbers and "facts and figures" do EVERYONE A FAVOR and make some attempt at having a clue BEFORE YOU POST!

FFS

EDIT: One of the sources in the following post
Another important thing to remember is that nicotine tolerance factors in. What might be lethal to someone who doesn't use nicotine might just give a buzz to a heavy user. Plus, it just isn't ethical to do LD50 tests on humans... :)

However, that being said, I'll echo previous comments and say that getting some e-liquid on your skin probably won't harm you. I suggest washing it off as soon as possible, but it really shouldn't be too much of a problem. I've gotten a drop of 36mg in my eye(by accident), and though it hurt like blue blazes, I didn't get much more than a slight buzz from it. I've had my share of spills, overfills, leaks, and usually nothing comes from it. Safety first, though!
 

CHUCKLEHEAD

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Going higher helped my cravings and didn't make me sick. I don't understand what some peoples problem seems to be with 36mg. Just because you didn't need it, doesn't mean that others don't need it.
I agree 100% with you ! I start my day off with coffee and vape 36mg 555 ! then my all day is 24mg !!!!!
 

olderthandirt

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Snus might help you out. Using it sparingly will help you get some of the chemicals (mostly MAOIs) that come from tobacco. It might be tobacco, but at least it isn't smoke.

I'm fairly new here, so could someone please tell me what snus is??

Good morning raven
Snus is tobacco that has been pasteurized. That is the really simple version.

There is a lot of information available here at ECF on this sub-forum:
Smokeless tobacco - e-cigarette-forum.com • The place for electronic cigarette reviews, news and chat

It is used either loose or in a portion, placed between upper lip and gum. A portion is simply the tobacco in a pouch. Snus does not create the same amount of saliva, nor does it contain the same amount of moisture as American style chew. This means there is usually no need to spit.

I added snus to my regimen almost 2 months ago. My daily intake of 3-4ml 36mg liquid vaped, has dropped to around 1ml or less since using snus.

EDIT: Never mind? You googled it? ah me....
 

umop apisdn

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Even 60 mg/mL is only 6%. A few drops of PURE freebase nicotine could kill you if get it on your skin (unlike those nano-toxic particles talked about earlier, nicotine readily absorbs through your skin - it likes both lipids and water). But even at such a small concentration of 6%, it's mixed with enough PG to save you. Your body will start metabolizing what you have in you before the rest has a chance to enter your system.

Sure, you'll likely get a nice buzz if you leave it on for a while, but it's not too much to worry about, especially at 24 mg.

And to whoever said something about juice being a "liquid snus"... I'm shocked at that idea, but at the same time, VERY curious. It definitely makes the name juice have more meaning behind it haha.
 

Cori

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Always a great idea to wash frequently! :lol: No seriously, while I don't panic I do wash my hands if for no reason other than it feels nice. :) I sometimes worry that I might have some on my hands when I pick up my small dog. So I make it a practice to wash my hands when I get it on me. Of course these days I'm down to 12mg so I don't worry so much. :D
 

Brewster 59

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Don't I know it!! I'm still smoking about 7 analogues a day because I can't handle the withdrawal symptoms (trying to decrease by 1 every few days). I wouldn't suggest a higher nicotine level either - I tried that and it made me feel ill. Vaping more made me feel ill too, so yes, you just have to deal with it, no matter how uncomfortable it is if you really want to quit. You might try some Valerian or other herbal anxiety remedy too.

Well I to experienced what you are describing however instead of using analogs I use snus. I hardly ever get a craving for an analog and get the alkaloids that I would otherwise be craving.
 

Kurt

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Ive experimented with some very potent compounds lethal in the single digit microgram range (an amount you cannot even see with the naked eye would kill 10+ people) and TRIED to simulate such a fatal skin exposure to an ultra-high concentration aqeous (distilled water) solution (10mg/ml) several times (whilst having a pre-loaded syringe of the suitable receptor antagonist handy of course). I was never able to kill and save myself. I left copious amounts of the solution on my skin for 10+ minutes. Without suitable solvent carriers, the transdermal absorption rate was dismal (and keep in mind this is microgram lethal so very very few molecules even need to absorb).


Theres almost no way your going to be able to transdermally administer a fatal dose of nicotine without utilizing special carrier agents to do so.

Woh!! As a chemist familiar with toxins of many types, what in God's name was this compound??? And why would you send the message that it is virtually impossible to kill yourself with nicotine? Have you read the postings of people that have tried to do their own nic extractions from tobacco, and getting violently ill? a drop of 24 mg on you may not do much, but several mL of 75 mg on you that you are not aware and thus don't wash off will cause some serious problems.

And BTW, what exactly is the antidote for serious nic poisoning? And how are you going to administer it if you are in convulsions, passing out, throwing up, and generally rendered nonfunctional? Several have posted such reactions to getting tobacco extractions on them.

And also BTW, how in God's name did you get such poisons? Are you in the CIA black ops? DARPA? Bioweapons? Just curious. Who are you to make these claims and to dangerously mislead the inexperienced like that, you of only 24 posts?

I've been in my field a long time. Never heard of such a thing. Please, educate me.
 

TWISTED VICTOR

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Woh!! As a chemist familiar with toxins of many types, what in God's name was this compound??? And why would you send the message that it is virtually impossible to kill yourself with nicotine? Have you read the postings of people that have tried to do their own nic extractions from tobacco, and getting violently ill? a drop of 24 mg on you may not do much, but several mL of 75 mg on you that you are not aware and thus don't wash off will cause some serious problems.

And BTW, what exactly is the antidote for serious nic poisoning? And how are you going to administer it if you are in convulsions, passing out, throwing up, and generally rendered nonfunctional? Several have posted such reactions to getting tobacco extractions on them.

And also BTW, how in God's name did you get such poisons? Are you in the CIA black ops? DARPA? Bioweapons? Just curious. Who are you to make these claims and to dangerously mislead the inexperienced like that, you of only 24 posts?

I've been in my field a long time. Never heard of such a thing. Please, educate me.

Hey, Kurt, easy does it. I don't know about him, but my exwife cooks in the same manner :D.
 

DVap

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Woh!! As a chemist familiar with toxins of many types, what in God's name was this compound??? And why would you send the message that it is virtually impossible to kill yourself with nicotine? Have you read the postings of people that have tried to do their own nic extractions from tobacco, and getting violently ill? a drop of 24 mg on you may not do much, but several mL of 75 mg on you that you are not aware and thus don't wash off will cause some serious problems.

And BTW, what exactly is the antidote for serious nic poisoning? And how are you going to administer it if you are in convulsions, passing out, throwing up, and generally rendered nonfunctional? Several have posted such reactions to getting tobacco extractions on them.

And also BTW, how in God's name did you get such poisons? Are you in the CIA black ops? DARPA? Bioweapons? Just curious. Who are you to make these claims and to dangerously mislead the inexperienced like that, you of only 24 posts?

I've been in my field a long time. Never heard of such a thing. Please, educate me.

I gotta call troll on this one. And a potentially dangerous one at that.
 

Kurt

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I second DVap.

Nanovapor, you had to know your post would cause serious head-turning, at the very least. Step up, please, and answer my questions in detail. They were NOT rhetorical questions. Let me try to be clearer:

What was the compound that < 1 microgram could kill 10 people?

How did you get it?

What was the antidote? And did you have someone there to administer it if you went under?

Was this a suicide attempt, or some sort of evil scientific study, and if so, who do you work for that you would have done this, and why?

Do you have some motive to make neophytes totally careless about their high-nic juices?

Surely you realize that if you have a patch on and have a smoke too, you can end up in the ER, or worse. And surely you realize that the FDA and other anti-vaping groups monitor this site, and would really love to see someone off themselves accidentally with nicotine juice, so it can make the news and scare everyone away from this valuable technology.

Its unusual for someone to become a supporting member after only a few posts, especially when your other posts are just the usual welcome greetings and how to make vapor go onto the surface of coffee...and then how safe it is to put an extremely potent poison on your skin! I do not call that support. I call that reckless. This is a public board. The FDA is itching to find a post like this to be able to say that we are an out-of-control lot of addicts who need to be protected from ourselves.

Step up, please. Don't worry, we'll be able to keep up.
 

kinabaloo

Vaping Master
ECF Veteran
That e-liquid is relatively slowly absorbed through skin is fortunate, because it gives time to wash it off (with soap). Nobody should think though that it will not be absorbed eventually, so always wash off even tiny amounts immediately. Same goes for surfaces, wipes, leaks, gloves, clothes, etc.

Cart leaks present the greater danger though and we do need better designs to avoid that possibility. Not having the liquid in the mouthpiece, and with the liquid 'sealed' (but refillable) such that only the expanded vapor can pass out through a valve or nozzle ...

If do get liquid in the mouth, spit it out as best as you can.

As with knives, power tools, electricity, drugs, cleaners, garden chemicals etc, respect the dangers and never get complacent. Don't take chances; that's how 'good drivers' get killed every day.
 
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