It will mix in VG but you'll need to heat the VG to thin it. 5 seconds in the microwave will thin it like water.
Use a 3ml syringe and remove the plunger, remove the needle and place your finger over the needle end of the syringe. Pour 1ml of powder into the plunger end filling to the 1ml mark then dump that into a 10ml glass bottle. Next add 7mls of VG to the bottle then 2 ml's distilled water. Heat for 5 seconds in the microwave uncapped (Careful when removing from the microwave it will be very hot) recap and shake the heck out of it. This will give you a 10% sweetener solution which is what you would
buy from a
vape vendor.
I myself don't like to use supermarket powered sweetener because it's not pure splenda, sacralos etc... It usually contains dextrose as well as other additives and fillers and is not as concentrated as what a vape
shop sells so keep that in mind. If you can find it already in a liquid form at the supermarket then that may be a better choice.