http://www.diychatroom.com/content/index.php?PLUCKarticleId=cba8487c-25f4-db02-d91f-e49104ccd8c1&PLUCKwhichPage=articlePage PROPYLENE GYLCOL

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Klimpt

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Apr 11, 2009
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Dublin, Ireland
Ok, well in the interests of thoroughness, I followed some links. Eventually wound up at a page from the Agency for Toxic Substances and Disease Registry. Put PG into search. Here are snips from the first few returns:


Ethylene Glycol and Propylene Glycol Toxicity: Key Concepts | ATSDR - CSEM
Ethylene Glycol and Propylene Glycol Toxicity
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* Ethylene glycol ingestion first affects the central nervous system (CNS). After a characteristic latent period, signs of inebriation may be followed by serious illness and even death, caused by toxic metabolites.
* Propylene glycol, which is much less toxic than ethylene glycol, is metabolized to compounds that are normal constituents of the citric acid cycle.
* No health effects have been reported in persons chronically exposed to ethylene glycol or propylene glycol at levels found in the environment.

Ethylene Glycol and Propylene Glycol Toxicity: What is Propylene Glycol | ATSDR - CSEM
Ethylene Glycol and Propylene Glycol Toxicity
What is Propylene Glycol?

Propylene glycol toxicity has been reported only rarely and in unusual circumstances. For example, toxicity may result from
* excessively large or rapidly infused intravenous injections of propylene glycol-containing medications, excessively large or rapidly infused intravenous injections of propylene glycol-containing medications (Louis, Kutt et al. 1967; Seay, Graves et al. 1997; Yorgin, Theodorou et al. 1997; Wilson, Reardon et al. 2000)
* prolonged dermal contact during treatment of burns

Those at special risk include
* neonates
* infants
* the elderly (Martin and Finberg 1970; MacDonald, Getson et al. 1987; Glover and Reed 1996; Peleg, Bar-Oz et al. 1998).

Increased sensitivity (Reprotext 2004) may be seen in people with pre-existing
* skin conditions
* eye conditions
* (possibly) allergic conditions


They also have a a toxological profile on PG here:
ATSDR - Toxicological Profile: Propylene Glycol

....

All this concerns me only very, very slightly, and only in one specific regard: we are all taking PG in a form that does not seem to have been envisaged in these kinds of reports, notwithstanding they are aware people breath it in from smoke machines and they don't seem hugely concerned by that. All in all, about 1% as scary as inhaling the smoke from burning leaves laced with ammonia and carbon monoxide. Yummy.
 
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