Placebo's can be used in various different ways and are sometimes used by knowing participants. Even though an e cig contains nicotine but none of the other 1000's of harmful chemicals it could be that an e cig mirrors the placebo in enough ways for e cigs to be considered placebo's. They kind of do the same thing, and i know not exactly the same thing, but there are enough similarities, aren't there ?. Tell me why you think an e cig should not be considered a placebo ?. Please try not to define the exact definition of a placebo because there isn't one. Maybe check wiki's definition of a placebo first. Try to make an informed opinion. Would it be right for the e cig to be defined in this way ?. If not how would "you" define an e cig in one word ?. If that's possible !. If not then explain in detail how the FDA should define e cigs ?.