I have had this problem with several highly recommended juices from reputable dealers. I have ruled out PG sensitivity and vendor issues as I have no problems with other juices from the same vendors or others with PG bases. I think the problem for me is with certain flavorings. Casablanca from BWB for instance, gives me an instant sore throat. If I continue to vape it I get blisters inside my mouth. Zillions of folks out there have no problem with this highly praised juice, so I mixed myself up a batch of pg/vg in a dropper bottle and used it to cut the Casablanca down by a third. It worked pretty well and the flavor s still there. I can get through a cart now with only a slight irritation, though I wouldn't push it past that. At least I don't have to throw it away. No matter how drooled over the juice or well loved the vendor, I have learned to order sample sizes.