New unique method to deliver nicotine

[TheBoogieman]

New smoking cessation therapy proves promising

Duke's new technology combines the vapor phase of pyruvic acid, which occurs naturally in the body, and nicotine. "When the two vapors combine, they form a salt called nicotine pyruvate," explains Rose. "This reaction transforms invisible gas vapors into a cloud of microscopic particles which is inhaled, just like a smoker inhales from a cigarette."

The Boogieman

 

[Kismayaz]

sounds interesting

 

[four2109]

Good find, Very interesting. Especially the last line.

Collaborators on the project included Turner, Murugesan, and Frederique M. Behm of Duke University Medical Center, Chris J. Wynne, of the Christchurch Clinical Studies Trust, Christchurch, New Zealand, and Murray Laugesen, of Health New Zealand Ltd., Christchurch, New Zealand.

Duke is getting the patent, but who is funding the research? Pharma or tobacco?

....Society for Nicotine and tobacco Research (SRNT) in Baltimore, MD
hmmm... more googling....

 

[Katmar]

That IS interesting. I can understand Dr.Laugeson undertaking such a study and perhaps finding an even better way than the current pg/vg method.

 

[Katmar]

I wonder if a mod can move this to E Cig News. I think it will get a lot more traffic and comments.

 

[Katmar]

Thanks, Elapid, Hopefully more people will read this and give their opinions.

 

[(So) Jersey Girl]

Duke is getting the patent, but who is funding the research? Pharma or Tobacco?

Most likely, the US taxpayer!

 

[Our House]

This sounds eerily similar to another recent study in which a similar product (ecig) didn't work under similar conditions (10 puffs per device, tests for plasma nicotine levels in the blood, asking users about reduced cravings, etc.).

Is it just coincidence that the non-pharma product "doesn't work" while the pharma product does?

 

[Vocalek]

It is mentioned in passing on the Health New Zealand site. Wish they would post the study details.

 

[DC2]

Interesting....

 

[TheIllustratedMan]

Pyruvic acid was mentioned to a member of the community as being a breakthrough to replace current electronic cigarettes. What the article doesn't say (and almost alludes to the negative on) is whether or not the method produces visible mist. It is most electronic cigarette users' opinions that the visible mist is a key component in the prolonged use of the device.
Indeed interesting, but is it viable?

 

[TropicalBob]

This is part of the evolution of future smoking. It's long been said that if e-cigs are allowed to mature, they will evolve into something we hardly recognize as today's product. And they'll work for all, without a need for other tobacco sources.

Ploom is also part of that future. So is this delivery method.

But SRNT is notoriously anti-ecig at the moment. You won't hear anything positive about our practice at that gathering. So don't take heart that this means some important group will be on the e-smoking bandwagon.

In fact, this might be viewed as ominous. It is a Big Pharma future product, probably prescription-only in the beginning, so money is at stake here. And the last paragraphs explain that its safety and efficacy must be proven (clinical trials) and it will be three to five years before it can be marketed. In the meantime, a ban on e-cigs would be in order for the FDA, since our safety and efficacy are unproven.

The FDA will say that approved, safe alternatives that are better than e-smoking will soon be available, so unapproved Chinese products with unregulated quality control cannot be allowed to remain on the market.

But ... we knew the future wasn't rosy. This is capitalistic evolution at play. Good to know, at least, that alternatives are being worked on. That has got to be better than "quit or die".

 

[Mister]

Patent application: DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT - Patent application
A reference to the new device by Dr. Laugesen: http://www.healthnz.co.nz/HNZSubmission_MASC_2010.pdf

 

[nojoyet]

Patent application: DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT - Patent application
A reference to the new device by Dr. Laugesen: http://www.healthnz.co.nz/HNZSubmission_MASC_2010.pdf

Thanks for these links.

Assuming he is referring to what we are now using, I find some encouragement from the second link here

"3)Research....Findings...with good safety profiles...the electronic nicotine cigarette on sale overseas..." and in the immediately following conclusions.

 

[rothenbj]

Thanks for these links.

Assuming he is referring to what we are now using, I find some encouragement from the second link here

"3)Research....Findings...with good safety profiles...the electronic nicotine cigarette on sale overseas..." and in the immediately following conclusions.

From my take, part of what he spoke about was what is currently available and part this three year in development, new device.

What I found interesting is that they have a goal of 2020 as the date to remove traditional cigarettes from the market. Something that supposedly can't happen in the U.S. Actually, I wonder if that will remain true over time. Once the government has a suitable replacement for cigarettes in terms of product and tax generation vehicle, I'm sure they will find a way to make them disappear.

Well maybe not completely disappear, just move them to the illegal side where they can imprison for use. Must keep that industry strong.

 

[FluffaPuff]

Read this today on WebMD...

New Nicotine Inhaler May Help Smokers Quit

 

[Vocalek]

There's one paragraph in the above linked story that I found irritating:

Rose says that although the device would be used to help people quit smoking entirely, it might also help people who are not ready to quit -- such as people self-medicating with nicotine for depression or schizophrenia.

Makes it sound as if the self-medicating folks would continue smoking tobacco cigarettes while using the device. But what they really mean is that folks who are not self-medicating would give up using all sources of nictoine, while the self-medicating would become long-term users of the device.

When are they going to "get it"? To "quit smoking" means to stop setting tobacco on fire and inhaling the smoke! It does not mean to "quit using nicotine entirely". If that's what they really mean, then that's what they should say!

I have quit smoking entirely! But I continue using my device, because that's what's best and healthiest for me.

 

[rothenbj]

That's the key public issue in my opinion Elaine. Nicotine and smoking have been made synonymous in many peoples' minds. That's even true in the smoking community. I've had smokers say "why bother" when I've explained that PVs only provide nicotine without the smoke.

It's amazing to me that twenty some years of a recurring sales pitch could have such an impact.