I would suggest to the community that you conduct your own radnomzed controlled clinical trial on the effects of e-smoking vs analogues. Granted it won't ge a strong study without financial backing but if may add fuel to you arguements against an FDA ban.
First, you'll want to research what' been done already and in simiilar studies with products such as wellbutrin, what were their primary endpoints? Criteria should include did you quit analogs? How much nicotine per day/week is now est in your system because of the change? Are your lung measurements (you can buy a simple pulmonary function test for astmha) better than your baseline? Long term effects, you won't be able to comment on. But did you cut nic down to 0 or have you substitued one vice for another? Did you quit e-cigs at the end of the study too? You'll need all listed side effects (adverse events) for your baseline analog period and then when you switch.
If there were a large number of people in the study, you coud help your industry to survive. You'll need to find an interested pulmonologist who does research, a statatician and if luck,a mediical writer at the minimum.
Remember, the FDA is drivin by seeing statistical changes in FUNCTION. So if 50% quit on e-cigs (and maybe stopped the eCigs later, that'be great); but if the quitting lead to less hospitalization for respiratory purposes, that' be extra strong.
Anyway, just a thought. If there's anyone out there willig to drive this process, I can give some advise along way. if you'd like.
First, you'll want to research what' been done already and in simiilar studies with products such as wellbutrin, what were their primary endpoints? Criteria should include did you quit analogs? How much nicotine per day/week is now est in your system because of the change? Are your lung measurements (you can buy a simple pulmonary function test for astmha) better than your baseline? Long term effects, you won't be able to comment on. But did you cut nic down to 0 or have you substitued one vice for another? Did you quit e-cigs at the end of the study too? You'll need all listed side effects (adverse events) for your baseline analog period and then when you switch.
If there were a large number of people in the study, you coud help your industry to survive. You'll need to find an interested pulmonologist who does research, a statatician and if luck,a mediical writer at the minimum.
Remember, the FDA is drivin by seeing statistical changes in FUNCTION. So if 50% quit on e-cigs (and maybe stopped the eCigs later, that'be great); but if the quitting lead to less hospitalization for respiratory purposes, that' be extra strong.
Anyway, just a thought. If there's anyone out there willig to drive this process, I can give some advise along way. if you'd like.
