PG is Used in Injectable Medications.

[Heavyrocker]

[h=5]One of the ingredents in Ecigs.



PG has been used as the aqueous-based chemical additive in asthma inhalers and nebulizers since the 1950s, with no serious side effects known. PG, because of its water-retaining properties, is the compound of choice for delivering atomized medication. It is also a common diluent for injectable medications, constituting 40 percent of the intravenous form of Phenytoin, an anti-seizure drug.[/h][h=5]constituting 40 percent of the intravenous form of Phenytoin, an anti-seizure drug.[/h]


Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties.[56] However, after coadministration with an MAOI, such as those found in tobacco, nicotine produces significant behavioral sensitization, a measure of addiction potential. This is similar in effect to amphetamine.[36]

 

[chellemmm]

And???????????

 

[Heavyrocker]

AND:

Vegetable Glycerin studies


Glycerol is one of the most benign organic liquids known to man. It is hype-allergenic, non-carcinigeic, non teratogenic and non-mutagenic. It is metabolized quite easily by a process called beta-oxidation. This process results in the production of CO2 and H2O and is a quite normal, common, and natural catabolic process.

The following is a few excerpts from a study called SIDS initial assessment profile of Glycerol Citation

Glycerol is of low toxicity when injested, inhaled, or in contact with skin
The NOACE for local irritant effects to the upper respiratory tract is 165 mg/m3
Glycerol is of a low order of acute oral and dermal toxicity with LD50 values in excess of 4000 mg/kw bw.
Glycerol has low potential to irritate the skin and the eye
Glycerol is not a skin sensitiser
Glycerol does not induce gene mutations in bacterial strains, chromosomal effects in mammalian cells or primary dna damage in vitro
Overall, glycerol is not considered to possess genotoxic potential
No effects on fertility and reproductive performance were observed
No further work is indicated by this study, because of the low hazard potential of this substance

- See more at: The safety of vegetable glycerin (VG) when inhaled through an electronic cigarette (e-cigarette). Studies on the effect of the inhalation of vegetable glycerin through a personal vaporizer.

 

[Penn]

When I first started, I asked 2 pharmacists (separate from each other) what they thought of ecigs. Neither really knew enough so said they didn't have an opinion yet (right there I knew each was worth getting a valid opinion). I told them the ingredients. Both propylene glycol and glycerin are used in the medical field (both have multiple uses but are ingredients in injections) and both pharmacists said there is nothing wrong with those.

The only negatives stated by them - both mentioned nicotine but agreed not much is truly known about it separate from tobacco, one mentioned the flavors may be an issue and the other mentioned the temperature of what is inhaled.

 

[Heavyrocker]

AND:

Nicotine Fact - It's Medically Proven to be Good for You!


Nicotine removed from cigarettes in its natural organic form is safe and non-toxic and medically proven to have health benefits, which are listed in this article.

Nicotine is part of the natural food chain.


Nicotine has been the victim of bad press due to its consumption in cigarette smoking but on its own, in organic form it is - Non toxic and as we have seen above can actually do you good which is a medically proven fact.

 

[Heavyrocker]

When I first started, I asked 2 pharmacists (separate from each other) what they thought of ecigs. Neither really knew enough so said they didn't have an opinion yet (right there I knew each was worth getting a valid opinion). I told them the ingredients. Both propylene glycol and glycerin are used in the medical field (both have multiple uses but are ingredients in injections) and both pharmacists said there is nothing wrong with those.

The only negatives stated by them - both mentioned nicotine but agreed not much is truly known about it separate from tobacco, one mentioned the flavors may be an issue and the other mentioned the temperature of what is inhaled.

They are only trained too dispense drugs.

 

[Penn]

They are only trained too dispense drugs.

No, they have advanced degrees that mean they should know a lot about the drugs they dispense, which those two clearly do. Both places I was at were compounding pharmacies, meaning they mix stuff instead of just distributing what they get from their suppliers.

 

[Heavyrocker]

No, they have advanced degrees that mean they should know a lot about the drugs they dispense, which those two clearly do. Both places I was at were compounding pharmacies, meaning they mix stuff instead of just distributing what they get from their suppliers.

Lol...even doctors today are basically drug dealers,they know didly squat about natural cures,all they know is pharma drugs.

 

[WattWick]

I'm having a hard time understanding what they mean with "nicotine in it's organic form is non-toxic". What is organic nicotine as opposed to what nicotine? Are there chemical differences?

I suppose they mean that eating potato won't kill you from nicotine poisoning. Extract "organic" nicotine from enough potatos, and you got a lethal toxin.... if I'm not entirely mistaken. Which wouldn't be a first.

 

[Heavyrocker]

What is organic nicotine as opposed to what nicotine? you asked:

Simple,as opposed too getting it from burning tobacco,you can extract it from the leaves instead.

 

[Penn]

Lol...even doctors today are basically drug dealers,they know didly squat about natural cures,all they know is pharma drugs.

That is a totally different statement from the one I commented on. Have a second look at your initial comment.

They are only trained too dispense drugs.

 

[Ref Minor]

Grease is used in suppositories, that doesn't mean it's healthy to inhale on a daily basis.

 

[rolygate]

Not sure how it goes in every country, but where I live (in the UK) it is generally recognised that if you want to know about drugs, and/or the effects of consuming any material with bioactivity, then you ask a pharmacist not a doctor. Pharmacists are specialists in drugs, doctors (or GPs as they are called here -general practitioners) are specialists in diagnosing and treating disease within the general community. 'Specialists' here are consultants or registrars at a hospital who specialise in a particular area.

I have been told several times by senior nurses that to find out about a drug or other consumed chemical you need to talk to a pharmacist not a doctor. Of course, there are pharmacists and there are pharmacists. As in every other field, not all are equal; but 100% of their daily work is concerned with drugs and consumable materials and this does not apply to a doctor.

 

[rolygate]

The wording used in that statement: "organic nicotine" is poorly chosen: all nicotine is 'organic' as its origin is a plant. The only non-organic nicotine is in a lab; synthetic nicotine has no practical uses as it is too expensive, has only 50% of the bioactivity of organic nicotine, and has no history of use in humans and is therefore probably not advisable to consume.

What they probably meant was 'pure nicotine' as against nicotine supplied in tobacco smoke, which is about the most impure form you could come up with (it is supplied in a mix at elevated temperature with multiple synergens, boosters and pyrolitic compounds). You couldn't design a more impure form of nicotine: it is specifically engineered not just for maximum effect but maximum boost.

There is no evidence that pure nicotine is addictive (in humans - animal nicotine models don't transfer to humans); indeed there is some evidence that it isn't.

And it is important to note that there is not one single clinical trial of nicotine in humans - all citations lead to smoking dependence or trials with ex-smokers, which are both irrelevant. Until there is some evidence that nicotine by itself is reinforcing (has potential for dependence), then all we can say at this time is that smoking is addictive (as it kills; to use the term 'dependence-creating implies that no harm results, as in: "Coffee is dependence-creating" - not 'addictive', because no measurable harm results).

We already know that nicotine consumption ad lib over decades is essentially harmless. Nothing of this kind, such as caffeine (coffee) or nicotine [1] can be described as harmless - this is impossible - but no measurable harm can be detected statistically at population level (and there is a mountain of data available).


[1] Meaning supra-dietary amounts (supplements to the normal dietary consumption of nicotine). Nicotine at the level found in the diet is assumed to be harmless or even beneficial (its sister compound nicotinic acid or niacin is vitamin B3 and shares most of its effects).

 

[Gary Mcroy]

That wouldnt change whether the nicotine is is organic or not, if its grown its organic if its made it a lab it would be synthetic. Setting a substance on fire doesn't change it from organic to non-organic....

 

[Gary Mcroy]

Sorry I posted that directly after reading "heavyrocker"s statement didnt notice people had already responded, but someone needed to, ha. There's enough bad information floating around.

 

[Heavyrocker]

That wouldnt change whether the nicotine is is organic or not, if its grown its organic if its made it a lab it would be synthetic. Setting a substance on fire doesn't change it from organic to non-organic....

They dont make synthetic nicotine,its extracted,big difference.

 

[SissySpike]

Cool So I can quit buying all these pesky delivery devices and get a IV drip fill'er up with juice and carry the bag in a back pack ! I think you might be on to something;-)

 

[Heavyrocker]

Cool So I can quit buying all these pesky delivery devices and get a IV drip and carry the bag in a back pack ! I think you might be on to something;-)

That would be no fun at all,i need TH and plumes of ''smoke'' and hand to mouth action.

 

[SissySpike]

That would be no fun at all,i need TH and plumes of ''smoke'' and hand to mouth action.

yea but...... ok you got me there;-)