Potential drugs developed to help curb smoking

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stols001

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I don't care what anyone else thinks about that enzyme and whether blocking it would be just fine or not. Honestly. I just think it is a very terrible idea, IN GENERAL, and especially with a smoker trying to quit but it's also psychological, sounds like a REALLY fun trip to the ER for nicotine overdose to me, personally.

While I am FAIRLY certain that I have many copies of that enzyme, I just really.... Antabuse anyone? Sure, it will stop you metabolizing nicotine, until YOU FALL OFF THE WAGON and smoke two packs like I WOULD probably DO, and then I'd get nicotine poisoning.

I swear to god, the "researchers" trying to "aid" the tobacco inflicted, it just REALLY looks like they are getting EVER more inventive in their attempts to KILL them.

I just can't freaking wait for the FDA studies, where suicidal thoughts, actions and KNOWN fatal ODs on nicotine will be ALL listed on the side effects sheet as "acceptable known reactions."

They can/could ONLY get away with this crud because it's addiction, like long term naltrexone depot therapy where parents do it to their underage KIDS and like DEATH and suicide is listed like a BILLION times.

Guess what naltrexone BLOCKS in FACT. Any and ALL endogenous endorphins, so sure, opiate action is blocked. So is the dang effects of sex, chocolate, and exercise.

I am APPALLED.


Etc.

Anna
 

bombastinator

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Interesting but I no longer smoke just vape and not really concerned about stopping vaping.

The FDA approved Chantix as a safe quitting drug and it isn't.
Chantix is a joke. It’s just Wellbutrin. a not real good antidepressant they renamed so they could keep the patent. It’s pretty safe as anti depressants go, but that’s not saying a great deal. It’s got all the problems of ramp up and ramp down that anti depressants have. It’s only up side is it doesn’t stomp on your libido quite as hard as some of the other anti depressants.
 
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Fredman1

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Over here in NZ its called Champix. Government funds it to stop smoking. I personally stopped 6 or more times using it. It was the only thing that could ever help me stop smoking. Side effect I got from it, was excessive dreaming...man I was an active sleeper. I also remember the last time I used it, I suffered from sleeplessness, and stopped using it.
Tried Zyban...didn't do anything to me.
 
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stols001

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'Opinion' or 'observation?'

Haha! I knew you were going to say that and I have an ANSWER. If N equals "all the folks who have an opinion but don't express it, and Y equals the subset of all the people who DO have one, the number Y could actually be identified, but the number N has to remain imaginary because obviously it's impossible to count those who don't express it because it REMAINS unexpressed. For all you know Y might be 3% of total folks with an option. Your "so many" implies a larger number than what might actually be fact, unless you want to back of from your claim and state that "so many" actually equals like 2 people. I suppose in your shoes I might want to make that argument, but it doesn't hold much water with me.

So yes, it is an opinion, not a fact. DEFINITELY opinion, unless you'd like to back up your claim somehow, but I'd say (personally) that it's like, unsubstantiated. Unless you want to do a study or something.

LOL it's not that I feel any concern at being someone who expresses an opinion, hence my claim that you are WRONG.

It also rubbed my "free speech" button the wrong way.

But you are definitely stating an opinion, not fact. That probably IS factual, unless you can convince me otherwise and good luck with that.

LOL.

Anna
 
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Cool_Breeze

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...Your "so many" implies a larger number than what might actually be fact,...

Anna

Without leaving out the aspect of 'time' which was implied by the original use of 'today,' suggests that more opinion is now being expressed than what was in the past. Can I prove that with numbers or equations..? I really don't care to attempt the exercise.

Are you of the 'opinion' that we are exposed to no more, or insignfiicantly more 'opinion' than we have been in the past?
 
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stols001

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I'm sure I could go back further, but I think we all know the phrase "Opinions are like...." first usage I found of this quote was by Milton R. Saperstein and he DIED in like, 1996, so I'm fairly certain that your "compared to today" OPINION is like, not correct. I am fairly certain that people have annoyed, entertained, amused, and occasionally disgusted each other with their opinions since the discovery of fire.

Pretty much after it was no longer necessary to expend 90% of ones energy NOT getting eaten by dinosaurs, and probably EVEN THEN, because I'm quite certain there were disagreements about how best NOT to get eaten by dinosaurs, so I am afraid that once again, I will have to disagree with that opinion. Etc.

Anna
 

Cool_Breeze

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'having opinion' vs. 'expressing opinion.' Does the internet expose us to a greater amount of expressed opinion (outside academia) than we might have experienced prior to forums and such? Are we getting more opinion in today's hyper-polarized environment?

Are you in this just for the sport of it?

It seems you are continuing to attempt to find me guilty of something.

Someone is attempting to employ a novel approach to circumstances regarding nicotine.

Knee-Jerk negative reaction comes easy.

If I am guilty of something, it is not anticipating wholly negative reaction to to the facts regarding someone's approach to address a matter.

I rest.
 
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stols001

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Well I'm sorry my intent was not to make you uncomfortable although it may have been a side effect.

I simply disagree.

If you don't understand the way this drug functions and the history of addiction blocking drugs, .perhaps that is why you consider it a "knee jerk" reaction.

The problem is that addiction is NOT purely physiological in nature, it is bio-psycho-social-psychological in nature. I have friends who have DIED thanks to naltrexone depo blocking therapy, and several people I know have NOT had a fantastic time on Antabuse, Chantix etc., and I feel IN PRINCIPLE that parents should not be allowed to depo naltrexone their children in the hopes that it will cause them to stop using certain substances.

This is an area of medicine I happen to feel strongly about, and the fact that it is being developed is "not promising," it is "rather frightening" actually. Because you can BLOCK an effect .physiologically, but if the user or said substance continues to crave and imbibe it psychologically, you can wind up with really ugly health consequences.

I do not care for the type of medicine this falls under, especially given the fact that misinformed or uncaring parents may well decide to involuntarily place their smoking or vaping teens on it, and the repercussions may be dire.

If you have an argument to make, make it (about the drug development and why it seems "promising to you.") Instead of talking about "knee jerk reactions" and shaming people for free speech..

Because, it certainly appears as if you did not enjoy it when I turned the tables did you? You sure didn't like being told that you, yourself, was making an opinion which you were and then my insistence that you back up said opinions with facts. I wasn't out to "get" you, but it should be noted that I ONLY stated the exact same thing that you did when condemning the free speech of others-- my opinion.

So, no offense and no, I didn't like it, and neither did you. That was my .point about free speech. It's pretty easy to "observe" what you did, but in that case, surely my "earlier" observations about this drug and its potential hazards were just that, too. Observations, based on my actual close reading of the text, comprehension of what "blocking drugs" do to the brain and the body, and everything else.

So, perhaps that will be a little bit more clear. I have seen people die from drugs SIMILAR in mechanism of action to THIS one, and my comments were directed from my past prior observational experience.

So either let free speech happen, or be more clear in your own opinions, observations, biases etc. We all have them. I do not dispute that. But, I'm not going to sit there and allow myself to believe that your opinions on free speech carry the weight of fact when they don't and are sort of sideways censorship, in truth.

And that is my final word on the topic.

Anna
 
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