I cannot say. I'm a very literal person. I read the question to be exactly what it says, "mix flavored base without nicotine then add it later." I have no idea if it is just flavoring, flavoring and PG, Flavoring and VG, flavoring and PG/VG, what the nicotine level ranges are, why you'd want to do such a thing, or any number of things. Just without then add later, so I went with the simplest answer, skip adding nicotine.
I've seen questions where folks just wanted to know how to mix their flavoring combo up together and use it as a single flavoring. I've seen questions where the person wanted to make all their mixes at 50% of a flavored base and the remaining half whatever they wanted. And all kinds of different versions of the rough concept. I try not to assume what the intent of the OP's question. Since the math behind this comes so easy to me, I am never sure I'm the right person to answer because I tend to miss stating details that I assume are well known concepts. Of the two questions I used as examples, the math is the same really, but the results are different. As usual with mixing math, you eliminate variables if you start with what you want to end up with, so starting with the desired end result makes things easier.
I guess I should have been more specific . If I make a 150ml mix of 70/30 PG/VG with flavor but no nicotine it would be PG 82.5ml, VG45ml. and flavor would be 22ml .Using 100mg 100%pg nic can I add it after I have made the original mix. Say I want 15ml at 18mg of nicotine could I just add 2.7ml of nic and the rest of the mix would be the original flavor mix that I made. So it would be 2.7ml of nic and 12.3ml of the original mix to get to 15ml. or would it weaken the flavor? I have been making juice for awhile and the only thing that changes when I change the nic level is the pg amount ,when making a 15ml bottle at 18mg nic with one flavor it's always 2.7ml nic 5.55ml PG 4.5ml VG and 2.25ml of flavor. Not sure if how I am explaning it makes any sense lol