I was freaked out in the beginning, so I got lower than 100 mg/ml, I started with 48 mg/ml.
It was kind of six of one half a dozen of the other honestly, because I needed more "nic juice."
I am clumsy, I get 100 mg/ml nic on my hands fairly frequently but it's not a big deal, honestly. I actually DON'T wear gloves on purpose so I know if I have some on me I can just wash my hands. Instead of wiping it everywhere.
So mainly like, I also use a baking pan to catch any spills and just leave it there until I'm done, wash any bottles as needed, and then wash the pan. I use gloves at that point.
Once you figure out your "usual" flavor percentage you can make nicotine base If you want, I make mine 20 mg/ml because I know I'm usually adding more or less 10% flavorings to the mix, and frankly if I need a smidge more flavor (or less) it's not even really going to be that noticeable to me. Etc.
You can do it. You have to work REALLY hard to get nic sick.
Nicotine POISONING is NOT what the antis even cite when they say that ecigs will kill you, because it's so ludicrous, honestly.
You aren't going to buy pure nic, because THAT STUFF will kill you, potential but anything at 100 mg/ml probably wouldn't. Heck if you accidentally made yourself a 60 mg/ml mix by accident you would NOTICE it and etc. But, you wouldn't die. Some people actually TARGET that strength.
Anna