ROFL I just ordred 48Mg in a 30Ml bottle

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The LD50 (Dosage to cease life in 50% of the population) for Nicotine is 40-60mg when systemically absorbed. Or as one poster above reported or 0.5-1.0mg/kg.

The average weight of the Human male is between 168 and 183 pounds of 76-83kg respectively. Therefor making their LD50 between 38mg-76mg for 76kgs and 41.5mg and 83mgs.

Reports have stated that while nothing is impossible, it is EXTREMELY difficult to overdose on nicotine via inhalation alone. However systemic absorbtion via the skin is quite fast and uber effective. Please be careful when handling your nic liquids, and when working with higher mg liquids always use a plastic dropper style bottle instead of the glass dropper vials to minimize the amount exposed too in the event of a spill.

Happy Vapping and Safe travels!
 
P

Phil River

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The LD50 (Dosage to cease life in 50% of the population) for Nicotine is 40-60mg when systemically absorbed. Or as one poster above reported or 0.5-1.0mg/kg.

The average weight of the Human male is between 168 and 183 pounds of 76-83kg respectively. Therefor making their LD50 between 38mg-76mg for 76kgs and 41.5mg and 83mgs.

Reports have stated that while nothing is impossible, it is EXTREMELY difficult to overdose on nicotine via inhalation alone. However systemic absorbtion via the skin is quite fast and uber effective. Please be careful when handling your nic liquids, and when working with higher mg liquids always use a plastic dropper style bottle instead of the glass dropper vials to minimize the amount exposed too in the event of a spill.

Happy Vapping and Safe travels!

Nuff said :thumb:
 

JustJulie

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I just thought the whole purpose was to go down in nicotine levels not up.

Different folks have different goals. For some, it's to reduce or eliminate nicotine. For others, however, they have little or no desire to give up nicotine--they just want to enjoy it in a less hazardous fashion. :)
 

Ridewithme38

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Different folks have different goals. For some, it's to reduce or eliminate nicotine. For others, however, they have little or no desire to give up nicotine--they just want to enjoy it in a less hazardous fashion. :)

I try to buy the Strongest Nic. juice possible...most of the time...you pay the same for 30ml of 48mg nic juice as 30ml of 16 mg nic juice...By cutting that 48 mg three times you get 90ml of 16mg nic juice for the same price you would have paid for 30ml of the 16 stuff...just makes good business sense....i just wish i could find stronger to cut down ever further
 

daniel2828

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There has been considerable discussion on the forum lately regarding the possibility of overdosing (by high nicotine content liquids, absorption through the skin, etc.), with occasional remarks about ultimately landing oneself in a hospital at best and under 6 feet of dirt at worst. But how likely is either, in the absence of purposely drinking this stuff or using it as a bug repellent on one's chest?

When we all had that first cigarette (damned that day!), I suspect most of us experienced--depending on our perseverance--at least one or all of the following symptoms: light-headedness, shakiness, dizziness (mild to extreme), and even nausea. I suspect that this was not the effect of introducing smoke into our lungs for the first time. I'm certainly no expert on the subject, but wasn't this our first experience with nicotine poisoning? And wouldn't we experience these symptoms again if, through mishandling or over-puffing, we were to begin overdosing (and thus catch ourselves long before we felt a need to dial 911)?

Certainly, the amount of nicotine inhaled from a cigarette is miniscule compared to the amount in a bottle of liquid. Or is it? According to cancer.org, an individual will inhale between 1 and 2 mg of nicotine per cigarette. Averaging 1.5 mg per cigarette, that's 30 mg of nicotine per pack (which I used to go through in a four-hour time period easily).

Now I have no intention of seeing if I can sip my bottle of 24 mg bottle of liquid over the next four hours to see if I am still able to stand afterward. But if cancer.org is correct (along with my math), it would certainly explain why I can get liquid on my fingers all day long and even in my mouth occasionally while not experiencing symptoms of nicotine poisoning.

In addition, I recently came across this, as related to a health advisory in Europe concerning the presence of nicotine in wild mushrooms:

"Due to the short biological half-life of nicotine in humans, it does not accumulate in the body and the most sensitive effect of nicotine is considered to be its pharmacological effect on the cardiovascular system."

In other words, while traces of nicotine do remain in our body over a period of hours (or even days for frequent smokers), it doesn't sit there for weeks on end until one day we wake up vomiting and barely able to stand (however, don't discount here the cumulative effect of nicotine on the cardiovascular system).

Anyway, I'm rambling. I THINK the initial intent of this post was to note that while nicotine is in fact an extremely dangerous poison and that we have a responsibility as adults to keep it well away from children and pets and to handle it ourselves with reasonable care, an occasional drop on the fingers or a leaky cartridge to the lips or even a hit off 48mg liquid isn't going to kill a seasoned post-ecig smoker out of the blue. If it did, I don't think this forum would be as active as it is.
 

DaMulta

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Different folks have different goals. For some, it's to reduce or eliminate nicotine. For others, however, they have little or no desire to give up nicotine--they just want to enjoy it in a less hazardous fashion. :)


Said very well


I bought some from a company in the US that is only 24Mg I vape 36Mg and love it.

I did buy some LorAnn Flavourings Strawberry Kiwi to try 48Mg uncut to see how I like it....but I bought it to increase E-Liquids that I buy that are under the 36Mg mark.


Also to the fact just to say it: I'm alive and kicking from my E-....!!! And that sucker well will put you on your ... to say the least.
 
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